8 results
management hematology oncology hemeonc behcet chronic cll differentiation disease emergencies hemophagocytic hlh leukemia leukostasis lymphocytic lymphohistiocytosis lysis ms multiple neurology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... Cathepsin G release → vascular ... common • Imaging: CXR ... : >3 symptoms, or ... #APML #diagnosis
Polycythemia Vera (PV) - Diagnosis and Management Summary Diagnostic Criteria: • Elevated hemoglobin and/or hematocrit AND •
Management Summary Diagnostic ... Criteria: • Elevated ... , signs, and complications ... transformation into AML ... #hematology
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Dehydration • Symptoms ... , dyspnea, +/- CXR ... WBC >100k, + lab signs ... #TLS #diagnosis ... #management #hematology
Multiple Sclerosis - Summary Multiple Sclerosis (MS) is an autoimmune-mediated neurodegenerative disease of the central nervous system
• Or brainstem syndromes ... Signs and symptoms ... criteria for MS ... Multiple Sclerosis Treatment ... management #neurology #treatment
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
meningitis), MCC CNS symptoms ... and diplopia) • Vascular ... Arthritis, AS Treatment ... #signs #symptoms ... #rheumatology #
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
with no early symptoms ... Physical Exam/Signs ... phenomenon CLL Diagnosis ... microglobulin Treatment ... • Richter’s Syndrome
Summary of Oncologic Emergencies Neutropenic fever: - Fever + ANC < 500 → start cefepime ± vancomycin (if
interventional radiology ... - Occurs after CAR-T ... : - Seen with AML ... (~20 %) and APL ... Oncology #HemeOnc #Diagnosis
Hemophagocytic Lymphohistiocytosis (HLH) High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
Presentation • Common Signs ... and Symptoms: ... Diagnostic Criteria ... of 8 HLH-2004 criteria ... #Management #Hematology
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