23 results
Multiple Sclerosis - Summary

Multiple Sclerosis (MS) is an autoimmune-mediated neurodegenerative disease of the central nervous system
Diagnosis - Based ... Signs and symptoms ... criteria for MS ... Treatment: • ... #neurology #treatment
Systemic Sclerosis (Scleroderma)
Multi-system autoimmune disease characterized by vasculopathy and progressive fibrosis of skin and internal organs
3
skin thickening Signs ... and Symptoms: ... myositis overlap • Vascular ... Scleroderma #SSc #rheumatology ... #diagnosis #signs
Polycythemia Vera (PV) - Diagnosis and Management Summary
Diagnostic Criteria:
 • Elevated hemoglobin and/or hematocrit AND
 •
Polycythemia Vera (PV) - Diagnosis ... Management Summary Diagnostic ... Criteria: • Elevated ... , signs, and complications ... #hematology
TRALI vs TACO - Transfusion Reactions
TRALI:
 • Epidemiology: 0.1% of transfused patientsl
 • Risk factors: Critical
ARDS to explain symptoms ... : 33% • Treatment ... fluid balance, and CXR ... : No • Treatment ... #diagnosis #comparison
Amyotrophic Lateral Sclerosis (ALS) Summary
ALS: combination of the clinical examination finding of amyotrophy with the pathologic
4) progressive muscular ... fasciculations Common Symptoms ... : months - Criteria ... : El Escorial criteria ... column Treatment
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Dehydration • Symptoms ... , dyspnea, +/- CXR ... WBC >100k, + lab signs ... Syndrome #TLS #diagnosis ... #management #hematology
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm
Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
- Differential Diagnosis ... Classic - Nodular Sclerosis ... pattern of spread, B symptoms ... Responsive to Treatment ... Amy Chung, MD, MSc
Gout (Gouty Arthritis) - MSK Radiology
Imaging Findings:
 • Eccentric soft-tissue densities surrounding the third proximal interphalangeal
Gouty Arthritis) - MSK ... circumscribed sclerotic ... mass and NO prior signs ... #diagnosis #msk ... #rheumatology
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Triggers: ATRA treatment ... Cathepsin G release → vascular ... common • Imaging: CXR ... : >3 symptoms, or ... Renal Failure Treatment
Adult Onset Still's Disease
Systemic inflammation with urticarial rash.
Rash: 
 • Nonpruritic, evanescent (correlates with time of
the chest/trunk Symptoms ... A nonpruritic macular ... Treatment - Mild ... : NSAIDS Treatment ... #rheumatology #