21 results
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Cathepsin G release → vascular ... - pulmonary opacities ... >3 symptoms, or> ... sepsis), PE, DAH, CHF ... #hematology #oncology
Atrial Fibrillation Overview

Symptoms:
Palpitations, light-headedness, dizziness, dyspnea, exercise intolerance, chest pain, near-syncope, syncope.

1. Why?
Cardiac:
• Valvular heart disease
•
Fibrillation Overview Symptoms ... Cardiac: • Valvular ... Decompensated HF ... Noncardiac: • Pulmonary ... #Fibrillation #Cardiology
Systemic Sclerosis (Scleroderma)
Multi-system autoimmune disease characterized by vasculopathy and progressive fibrosis of skin and internal organs
3
and Symptoms: ... ), PAH (pulmonary ... myositis overlap • Vascular ... Scleroderma #SSc #rheumatology ... #diagnosis #signs
Heart failure with Reduced Ejection Fraction (HFrEF)
Clinical Presentation
1. Typical symptoms: dyspnea, orthopnea paroxysmal noctumal dyspnea, fatigue,
Typical symptoms ... Chest x-ray: signs ... → no signs of CXR ... coronary artery disease ... #management #cardiology
Rheumatoid Arthritis - Signs and Symptoms
 • Ocular: Keratoconjunctivitis sicca, Episcleritis, Scleritis, Scleromalacia perforans
 • Pulmonary:
Rheumatoid Arthritis - Signs ... and Symptoms • ... Scleromalacia perforans • Pulmonary ... #Symptoms #diagnosis ... #rheumatology
Cryofibrinogenemia Summary

Cryofibrinogenemia Epidemiology:
 • 40-70 years with a modest female predominance

Cryofibrinogenemia:
 • The precipitation of a
Cryofibrinogenemia Symptoms ... Hyperviscosity, - Vascular ... thrombophlebitis, pulmonary ... Cryofibrinogenemia Diagnosis ... #rheumatology #
Rheumatoid arthritis (RA): Extra-articular manifestations
Skin: 
 • Inflammation of skin (esp. over areas of stress) forms
pleural effusion on CXR ... interstitial lung disease ... /pulmonary fibrosis ... pathophysiology #signs ... #symptoms #diagnosis
Increased pulmonary venous pressure is related to the pulmonary capillary wedge pressure (PCWP) and can be
Increased pulmonary ... related to the pulmonary ... features on the chest ... #Diagnosis #Radiology ... #CHF #CXR #Stages
Optic Neuritis - Diagnosis and Management
 • Epidemiology: Female (75%), 18-50 years,
caucasian
 • Symptoms: Moderate visual
caucasian • Symptoms ... Unilateral • Signs ... lesions (b) • CSF ... other auto-immune diseases ... Management #treatment #rheumatology
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
Presentation: Systemic Symptoms ... purpura: Strong sign ... pulse deficits vascular ... • Progressive symptoms ... #Rheumatology