48 results
Manifestations of IgG4-related disease by organ system.
 The most common primary disease features are indicated in
of IgG4-related disease ... by organ system ... #Organs #Systems ... #Diagnosis #Hematology ... #Signs #Symptoms
Systemic Sclerosis (Scleroderma)
Multi-system autoimmune disease characterized by vasculopathy and progressive fibrosis of skin and internal organs
3
autoimmune disease ... skin thickening Signs ... myositis overlap • Vascular ... Scleroderma #SSc #rheumatology ... #diagnosis #signs
Parkinson's Disease - Signs and Symptoms
Systemic: Tremor and Slowness, Impaired balance, Small Handwriting, Sleepiness, Trouble Moving
Parkinson's Disease ... - Signs and Symptoms ... Systemic: Tremor ... #Signs #Symptoms ... #neurology
SNOOP mnemonic may catch potentially life-threatening headaches
Systemic signs and disorders
Neurologic symptoms
Onset new or changed & patient
life-threatening headaches Systemic ... signs and disorders ... Neurologic symptoms ... mnemonic #headaches #Differential ... redflag #dangerous #neurology
Systemic Lupus Erythematosus (SLE): Musculoskeletal Manifestations

 • Immune Complex Deposition
    - Arthralgia, Arthritis
Systemic Lupus Erythematosus ... trabecular thinning -> Avascular ... Erythematosus #SLE #MSK ... pathophysiology #signs ... #symptoms #diagnosis
Causes of Dizziness - Vertigo - Differential Diagnosis Algorithm
True Vertigo - Illusion of Rotary Movement
Peripheral Vestibular
Dizziness - Vertigo - Differential ... • Meniere's Disease ... symptoms/signs, ... Glomus Tumors - Vascular ... #Differential #
Causes of Low Back Pain - Differential Diagnosis
Intrinsic Spine: Lumbar strain, Herniated nucleus pulposus, Compression fracture,
, spondylosis Systemic ... Connective tissue disease ... Referred: • Vascular ... cholecystitis; • Neurologic ... #primarycare #msk
Systemic Lupus Erythematosus - Diagnosis
Manifestations:
 - Arthritis 69%
 - Malar rash 40%
 - Fever 36%
 -
Systemic Lupus Erythematosus ... autoantibodies #signs ... #symptoms #mimickers ... #differential # ... rheumatology
Multiple Sclerosis - Summary

Multiple Sclerosis (MS) is an autoimmune-mediated neurodegenerative disease of the central nervous system
Examination: • UMN signs ... Clonus, Babinski’s sign ... • Lhermitte’s sign ... pupillary defect SIGNS ... Signs and symptoms
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Clinical Features of Systemic ... pain (20%) Renal disease ... erythematosus #signs ... #symptoms #diagnosis ... #rheumatology