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diagnosis signs arthritis erythematosus lupus workup algorithm cardiology management pain approach classification complications hematology monoarthritis monoarticular neurology pathophysiology polyarthritis polyarticular
Joint Disorders - Differential Diagnosis Algorithm Monoarthritis • Septic • Crystalline - Gout
Joint Disorders ... - Differential Diagnosis ... Erythematosus (SLE ... should have other symptoms ... #Disorders #msk
Systemic Lupus Erythematosus (SLE): Musculoskeletal Manifestations • Immune Complex Deposition - Arthralgia, Arthritis
Systemic Lupus Erythematosus ... (SLE): Musculoskeletal ... #MSK #Musculoskeletal ... pathophysiology #signs ... #symptoms #diagnosis
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Lupus (SLE) General ... phenomenon (20%) Joints ... Arthritis in small joints ... #signs #symptoms ... #diagnosis #rheumatology
Systemic Sclerosis (Scleroderma) Multi-system autoimmune disease characterized by vasculopathy and progressive fibrosis of skin and internal organs 3
and Symptoms: ... Musculoskeletal: joint ... myositis overlap • Vascular ... Scleroderma #SSc #rheumatology ... #diagnosis #signs
Approach to Joint Pain - Diagnostic Framework 1) Chronicity 2) Inflammatory vs Non-Inflammatory 3) Number of Joints Involved 1) Chronicity:
Non-bloody: OA, avascular ... Chronic = RA, SLE ... #Joint #Pain #MSK ... #rheumatology # ... approach #workup #differential
Approach to Joint Pain - Arthritis Differential Diagnosis Framework Inflammatory Versus Noninflammatory Pain • Is it inflammatory
Pain - Arthritis Differential ... Mechanical/degenerative disorders ... noninflammatory Signs ... constitutional symptoms ... #Diagnosis #MSK
Systemic Lupus Erythematosus - Diagnosis Manifestations: - Arthritis 69% - Malar rash 40% - Fever 36% -
Systemic Lupus Erythematosus ... autoantibodies #signs ... #symptoms #mimickers ... #differential # ... rheumatology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... permanent alopecia Differential ... Arthritis: • Joint ... arthropathy • 90% joints ... Induced Lupus: • Symptoms
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
context of other symptoms ... erythematosus (SLE ... Lymphoproliferative Disorders ... ANA #patterns #rheumatology ... #diagnosis #differential
Approach to Joint Pain History: Is the pain from: • Joint • Adjacent bursa • Tendon • Ligament • Bone • Muscle • Referred from
Approach to Joint ... or nerve root Symptoms ... osteopetrosis, avascular ... #Pain #MSK #rheumatology ... approach #workup #differential
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