21 results
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
platelet disorders, vascular ... Etiology: • Vascular ... Disruptions in vascular ... #Diagnosis #hematology ... #rheumatology #
Causes of Peripheral Weakness without Sensory Changes - Differential Diagnosis Algorithm
No Objective Weakness
 • Cardio-pulmonary disease
Weakness • Cardio-pulmonary ... • Progressive muscular ... Neuropathy • Spinal Muscular ... Polymyositis • Duchenne Muscular ... Peripheral #Weakness #Neurology
Causes of Pleural Effusion - Differential Diagnosis Algorithm
Transudate - Hydrostatic
 • Congestive heart failure
 • Constrictive
Pleural Effusion - Differential ... Malignancy • Pulmonary ... embolism • Collagen vascular ... Pleural #Effusion #Pulmonary ... Diagnosis #Algorithm #Hepatology
Paraproteinemias

Entities That Can Feature A Monoclonal Protein/M Component:
• MM
• WM
• MGUS
• MGCS
• MGRS
• Splenic Marginal Zone
et diutinum Neurologic ... Hypergammaglobulinemic macular ... (Thrombosis in vascular ... Paraproteinemias #Hematology ... #Monoclonal #Differential
Approach to the Hypotensive Patient - Differential Diagnosis Framework for Hypotension

Blood Pressure = Heart Rate x
Hypotensive Patient - Differential ... Volume x Peripheral Vascular ... inadequate cardiac output ... • Sick sinus syndrome ... depletion • Pulmonary
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
fraction < 20% Differential ... abnormalities • Muscular ... hepatitis • Pulmonary ... management #treatment #rheumatology
Weakness - Differential Diagnosis Framework

Approach To Weakness:
 • Non-neuromuscular disorder (Cardiac, pulmonary etc)
 • CNS ->
Weakness - Differential ... disorder (Cardiac, pulmonary ... myositis • Genetic: Muscular ... myopathies, the muscular ... #Diagnosis #neurology
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... Cathepsin G release → vascular ... Imaging: CXR- pulmonary ... initiation • Differential ... diagnosis #management #hematology
Thiamine Deficiency - Differential Diagnosis Framework and Clinical Manifestations

Causes of Thiamine Deficiency:
 • Poor intake:
	- Diets
Thiamine Deficiency - Differential ... HF • Moderate pulmonary ... Beri: - High output ... Tachycardia - High output ... AV shunt, renal vascular
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
Behçet's Syndrome ... skin injury) • Neurologic ... and diplopia) • Vascular ... Behcet disease) Differential ... signs #symptoms #rheumatology