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diagnosis differential hematology algorithm antiphospholipid apml arterial cardiology cryofibrinogenemia differentiation embolism endocarditis hypercoagulable infectiousdiseases management nonpalpable oncology palpable pathophysiology purpura
Dyspnea - Differential Diagnosis Framework Cardiovascular Causes of Dyspnea: • Myocardium: - Heart failure - CAD/ACS - Valvulopathy • Electrical: -
Causes of Dyspnea ... Hepatopulmonary syndrome ... Guillain Barre - ALS ... Transverse myelitis • Hematology ... #pulmonary
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Kasabach-Merritt syndrome ... - PNH - APLS ... Differential #Diagnosis #hematology ... #rheumatology # ... #nonpalpable #dermatology
Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework VENOUS THROMBOSIS • Acquired Risk Factors: - >48 hours
Hyperviscosity, TTP, APLS ... • Nephrotic Syndrome ... coagulation and other causes ... pathophysiology #hematology ... differential #diagnosis #vascular
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... Incidence: common in APL ... Cathepsin G release → vascular ... Imaging: CXR- pulmonary ... diagnosis #management #hematology
Endocarditis - Overview and Differential Diagnosis Framework Who? Infectious: • Pre-existing valvular disease • Prosthetic valve • Congenital heart disease • IV
Hypercoagulable (APLAS ... heart failure • Dyspnea ... Cerebral > Splenic, Pulmonary ... Cholesterol emboli syndrome ... Septic emboli cause
Cryofibrinogenemia Summary Cryofibrinogenemia Epidemiology: • 40-70 years with a modest female predominance Cryofibrinogenemia: • The precipitation of a
Hyperviscosity, - Vascular ... thrombophlebitis, pulmonary ... cryoglobulins • Negative causes ... Antiphospholipid syndrome ... #hematology
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
pulse deficits vascular ... affects the skin, neurologic ... cognitive impairment, neurologic ... tract, and often causes ... Differential #Diagnosis #Rheumatology
Antiphospholipid Syndrome (APLS) Testing - Hypercoagulable Workup Algorithm INDICATIONS FOR TESTING: • Vascular thrombosis
Antiphospholipid Syndrome ... (APLS) Testing ... FOR TESTING: • Vascular ... maternal chromosomal causes ... Algorithm #diagnosis #hematology
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