14 results
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... Kasabach-Merritt syndrome ... Gardner-Diamond syndrome ... #Diagnosis #hematology ... #rheumatology #
Causes of Bone/Joint Pain in Sickle Cell Disease
Vaso-occlusive pain:
 • Mechanism: ischemic pain
 • Can present
Causes of Bone/Joint ... Avascular necrosis ... • Differentiate ... #diagnosis #causes ... #hematology
Approach to Joint Pain - Diagnostic Framework

1) Chronicity
2) Inflammatory vs Non-Inflammatory
3) Number of Joints Involved

1) Chronicity:
Approach to Joint ... Non-bloody: OA, avascular ... Like in this case ... #rheumatology # ... approach #workup #differential
Approach to Joint Pain - Arthritis Differential Diagnosis Framework

Inflammatory Versus Noninflammatory Pain
 • Is it inflammatory
Pain - Arthritis Differential ... weeks) Can Be Caused ... - Autoimmune Rheumatologic ... #pain #Differential ... Diagnosis #MSK #rheumatology
Pulmonary Pathology and Associated Lung Ultrasound Findings
Pneumothorax:
 - No lung sliding/barcode sign
 - Lung point (hard
Associated Lung Ultrasound ... sign - Lung point ... pleura in severe cases ... Respiratory Distress Syndrome ... #pulmonary #differential
Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework

VENOUS THROMBOSIS

 • Acquired Risk Factors:
	- >48 hours
• Nephrotic Syndrome ... coagulation and other causes ... pathophysiology #hematology ... #differential # ... diagnosis #vascular
Paraproteinemias

Entities That Can Feature A Monoclonal Protein/M Component:
• MM
• WM
• MGUS
• MGCS
• MGRS
• Splenic Marginal Zone
Scleromyxedema (CNS+GI+CVS+joints ... Hypergammaglobulinemic macular ... (Thrombosis in vascular ... Paraproteinemias #Hematology ... #Monoclonal #Differential
Causes of Neutropenia - Differential Diagnosis
Neonate:
 - Infection - by far the most common cause
 -
- Differential ... neutropenia, Kostmann syndrome ... Chediak-Higashi syndrome ... #Neutropenia #differential ... #hematology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
permanent alopecia Differential ... Non-autoimmune rheumatologic ... Arthritis: • Joint ... arthropathy • 90% joints ... Erythematosus #Diagnosis #Rheumatology
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA)

Skin involvement in granulomatosis with polyangiitis (GPA) is common and
GPA causes disease ... surfaces of the joints ... reticularis Differential ... • Goodpasture syndrome ... rash #diagnosis #rheumatology