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diagnosis management syndrome differential lupus erythematosus hepatology infectiousdiseases signs summary symptoms systemic vasculitis algorithm alkaline alp als amyotrophic bcnie behcet
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
) Clinical Manifestations ... Cerebrovascular Disease ... , PRES Pathophysiology ... #CNS #neurology ... #rheumatology #
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
40, F:M 9:1 • Clinical ... Positive in 60-80% of cases ... life-threatening • Treatment ... Evolution: Chronic disease ... Management #Summary #rheumatology
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
to 1:1 F:M • Clinical ... 40, F:M 9:1 • Clinical ... life-threatening • Treatment ... Evolution: Chronic disease ... comparison #table #rheumatology
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Lymphohistiocytosis (HLH) Pathophysiology ... : SLE+++, Adult-onset ... Still disease, ... Drugs, Unknown cause ... #summary #rheumatology
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
skin injury) • Neurologic ... and diplopia) • Vascular ... Oral aphthae : SLE ... Arthritis, AS Treatment ... signs #symptoms #rheumatology
Posterior Reversible Encephalopathy Syndrome (PRES) Overview Clinico-Radiological Syndrome, characterized by: • Headache • Seizures • Altered mental
may precede the neurologic ... Shock, Autoimmune disease ... Etiology: • Pathophysiology ... cortical lesions • Vascular ... • Treatment of
Central Retinal Artery Occlusion: Pathogenesis and clinical findings • Inflammatory Disease: (i.e. GCA, SLE, GPA) ->
Pathogenesis and clinical ... • Inflammatory Disease ... GCA, SLE, GPA) - ... retinal edema caused ... Occlusion #CRAO #pathophysiology
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
• They can cause ... Vascular Sludging ... Syndrome: • Clinical ... • Autoimmune diseases ... classification #rheumatology
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
protein C and S Pathophysiology ... organ damage Clinical ... • Severe Liver Disease ... Treat primary cause ... #hematology
Clarkson’s Disease - Capillary leak syndrome Epidemiology: Roughly 150 published cases, Median age 50 years, No sex
150 published cases ... Relapsing-remitting course +++ Clinical ... IVIg) • Limit vascular ... spacing of IVIg cures ... #rheumatology
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