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diagnosis differential management hematology algorithm bruising syndrome approach arthritis behcet cerebritis classification cns cryofibrinogenemia cryoglobulinemia cryoglobulins cva erythematosus hemoptysis hemorrhage
Causes of Bleeding / Bruising - Differential Diagnosis Algorithm Thrombocytopenia - Quantitative Defect • Decreased Production •
Causes of Bleeding ... Vascular System ... TeIangiectasia Vascular ... • Steroids • Vasculitis ... #Hematology
Hemoptysis - Differential Diagnosis Framework Massive Hemoptysis: >150-300 mL in 24h Airway disease: • Bronchitis, Bronchiectasis, Malignancy
in 24h Airway disease ... Autoimmune: ANCA-Assoc vasculitis ... Heart failure Vascular ... Nasopharyngeal bleeding ... Diagnosis #pulmonary #causes
Causes of Intracerebral Hemorrhage (ICH) - Differential Diagnosis Algorithm Hypertension: • Essential Hypertension (Aneurysm) • Drugs (Cocaine,
Amphetamines) Vessel Disease ... Angiopathy • Vascular ... • Aneurysm • Vasculitis ... • Trauma • Bleeding ... #Stroke #CVA #Neurology
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
pulse deficits vascular ... affects the skin, neurologic ... cognitive impairment, neurologic ... tract, and often causes ... Differential #Diagnosis #Rheumatology
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
• They can cause ... Cryoglobulins Cause ... Vascular Sludging ... • Autoimmune diseases ... classification #rheumatology
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
, small-vessel vasculitis ... skin injury) • Neurologic ... and diplopia) • Vascular ... Arthritis, AS Treatment ... signs #symptoms #rheumatology
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Cerebrovascular Disease ... autoantibodies that will cause ... inflammation, leading ... Erythematosus #SLE #CNS #neurology ... #rheumatology #
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework == Quantitative or Qualitative defect in
• Disorders of vascular ... discern these causes ... Disruption in vascular ... integrity == • Vasculitis ... Differential #Diagnosis #Hematology
Cryofibrinogenemia Summary Cryofibrinogenemia Epidemiology: • 40-70 years with a modest female predominance Cryofibrinogenemia: • The precipitation of a
Hyperviscosity, - Vascular ... Paradoxical spontaneous bleeding ... malignancies, vasculitis ... cryoglobulins • Negative causes ... Cryofibrinogenemia #diagnosis #rheumatology
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
) • Cutaneous vasculitis ... : 2% Systemic Vasculitis ... phenomenon (16%) MSK ... Adenocarcinoma Treatment ... Sjogrens #Syndrome #Rheumatology
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