41 results
Parinaud's Syndrome
What?
 - Impaired upgaze
 - Light-near dissociation
 - Convergence retraction nystagmus
 - Eyelid retraction (Collier's
Parinaud's Syndrome ... retraction (Collier's sign ... → "setting sun sign ... " - Vascular disease ... diagnosis #pineal #neurology
Parinaud's syndrome
What?
 • Light-near dissociation (tectal pupils)
 • Convergence retraction nystagmus
 • Eyelid retraction (Collier's sign)
Parinaud's syndrome ... retraction (Collier's sign ... "setting sun" sign ... • Vascular disease ... #neurology #diagnosis
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
→ Refer to hematology ... for workup, including ... Rebound effect from treatment ... Inflammatory Conditions: Rheumatologic ... Kawasaki, Nephrotic syndrome
Autoimmune Myositis
Necrotizing myopathy is associated with higher CK levels, greater level of muscle weakness, less systemic
heliotrope rash, Shaw sign ... , holster sign, ... anti-synthetase syndrome ... after 2 years of treatment ... Myositis #diagnosis #rheumatology
Behcet's Syndrome - Treatment
Ulcers:
 • Treatment: Topical steroids
 • Prevention: Colchicine
 • Azathioprine for refractory disease
Arthritis:
Behcet's Syndrome ... : • Treatment: ... immunosuppressive meds) Vascular ... Behcets #disease #Syndrome ... #pharmacology #rheumatology
Major neurocognitive disorders (MNCD): Diagnosis and workup 

1) Clinical diagnosis Cognitive impairment + loss of autonomy
2)
Diagnosis and workup ... the diagnostic workup ... Aphaso-apraxo-agnosia syndrome ... (parkinsonian signs ... Frontal atrophy Vascular
Eosinophil Disorders Testing Algorithm
INDICATIONS FOR TESTING:
 • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
evaluation or workup ... 1,500 cells/µL Workup ... glucocorticoid treatment ... organ-specific signs ... Differential #diagnosis #hematology
Acute Spinal Cord Injuries: Pathogenesis and clinical findings
 • Anterior Cord Syndrome -> Anterior spinal artery
Anterior Cord Syndrome ... injury, often from vascular ... • Central Cord Syndrome ... pathophysiology #signs ... #orthopedics #neurology
Systemic Sclerosis (Scleroderma)
Multi-system autoimmune disease characterized by vasculopathy and progressive fibrosis of skin and internal organs
3
skin thickening Signs ... myositis overlap • Vascular ... Scleroderma #SSc #rheumatology ... #diagnosis #signs ... symptoms #testing #workup
Acute Kidney Injury - AKI Workup Algorithm and Differential Diagnosis
Baseline Investigations: full blood count with differential,
Kidney Injury - AKI Workup ... clinical context and signs ... • Cardio-renal syndrome ... #Injury #AKI #Workup ... Differential #Diagnosis #nephrology