44 results
Vasopressors - Charted by Vasoconstriction, Vasodilation, and Inotropy
 - Dobutamine
 - Milrinone 
 - Vasopressin
 -
Vasopressors - Charted by Vasoconstriction ... #Vasopressors #Vasoconstriction
Hepatorenal Syndrome - Diagnosis and Management Summary
Who gets HRS?
 • Decompensated cirrhosis
 • Typically with existing
Splanchnic/extrarenal vasoconstriction ... agonist of a1 (↑ vasoconstriction ... agonist, Splanchnic vasoconstriction ... regardless of vasoconstrictor
Hepatorenal Syndrome (HRS)

Definition:
• Functional, potentially reversible kidney impairment.
• Occurs in advanced liver disease: cirrhosis, severe alcoholic
perfusion + ↑ renal vasoconstriction ... • Renal vasoconstriction ... substituted as the vasoconstrictor ... • Vasoconstrictor
Pharmacological Treatment of Hepatorenal Syndrome (HRS)

Midodrine - Alpha agonist incr blood pressure incr renal perfusion pressure
Vasoconstriction ... Systemic vasoconstriction
Hepatorenal Syndrome Treatment
Volume expansion: 
 • Albumin (typical dose = 1g/kg on day 1 +/- day
oral systemic vasoconstrictor ... selective splanchnic vasoconstrictor
Major Physiological Effects of Angiotensin II

Altered Peripheral Resistance
I. Direct vasoconstriction
II. Enhancement of peripheral noradrenergic
neurotransmission:
  A.
Direct vasoconstriction ... Direct renal vasoconstriction
Stroke - Differential Diagnosis Algorithm and Management
Hemorrhagic:
 • Intracerebral: HTN, Cerebral Amyloid Angiopathy, Trauma, Bleeding Diathesis,
Atherosclerosis, Dissection, Vasoconstriction
Staging of Skin Mottling

Mottling is less sensitive, but more specific for hypoperfusion and elevated mortality (figure
active endogenous vasoconstriction
Raynaud's Syndrome - Washing off under hot water.
Raynaud phenomenon is an exaggerated vasoconstrictive response of the
an exaggerated vasoconstrictive
Raynaud's Syndrome - Washing off under hot water wath.

Raynaud phenomenon is an exaggerated vasoconstrictive response of
an exaggerated vasoconstrictive