20 results
Mechanism of Action for Common Diabetes Medications

 • SGLT2i (Dapagliflozin)
 • TZD (Pioglitazone)
 • Biguanides (Metformin)
Common Diabetes Medications ... Meglitinides • GLP-1 Receptor ... #Diabetes #Medications ... #pharmacology #pathophysiology ... #endocrinology
Diabetes Pathophysiology and Medication Targets

The ominous octet is one concept that summarizes the different pathophysiologic pathways
Diabetes Pathophysiology ... and Medication ... used diabetes medications ... #Medication #Targets ... #Drug #Endocrinology
Vasopressors and Inotropes - Pharmacology Summary
Vasopressors
Phenylephrine (alpha-1)
 • Increases BP, SVR
 • Risk of reflex bradycardia
Vasopressors and ... Pharmacology Summary Vasopressors ... septic shock Vasopressin ... Dose dependent receptor ... Summary #management #medications
Pharmacological Treatment of Hepatorenal Syndrome (HRS)

Midodrine - Alpha agonist incr blood pressure incr renal perfusion pressure
vasodilatation Vasopressin ... - V1 receptor agonist ... Terlipressin - Vasopressin ... #Pharmacology #Medications
Diabetes Medications Summary Table
Insulin
Lifestyle modifications
Metformin
Sulfonylureas
GLP-1 receptor agonists - ↓ major adverse CV events
TZDs
DPP-4 inhibitors
SGLT2 inhibitors -
Diabetes Medications ... Sulfonylureas GLP-1 receptor ... #diabetes #medications ... comparison #management #endocrinology
Graves’ Disease: Pathogenesis and Clinical Findings
B & T lymphocyte mediated autoimmunity attack TSH receptor -> Continuous
autoimmunity attack TSH receptor ... of thyrotropin receptor ... GravesDisease #pathophysiology ... #endocin #endocrinology
Mechanisms of Drug-Induced Hyperkalemia 
 • Direct renin inhibitor (Aliskiren)
 • Renin release inhibition (NSAIDs, Beta-Blockers)
Angiotensin II Receptor ... differential #diagnosis #pathophysiology ... pharmacology #potassium #medications
Diuretics and Agents Regulating Renal Excretion

Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide)
 • Glaucoma
 • Epilepsy
 • Altitude
Association class IV) Vasopressin ... Receptor Agonist ... (Vasopressin) ... bleeding disorders Vasopressin ... #Pharmacology #Medications
Management of SIADH
Treat underlying cause:
 • Causes can include pain, primary lung pathology, post-operative phenomenon, medications,
post-operative phenomenon, medications ... bolus of 0.9% NS Vasopressor ... receptor antagonists ... • Blocks ADH receptor
Benign Prostatic Hyperplasia: Pathogenesis and Medications
Aging
 -> Increased Testosterone -> Testosterone metabolized into DHT by type
Pathogenesis and Medications ... binds to androgen receptor ... LUTS - LHRH receptor ... Hyperplasia #Prostate #Pathophysiology ... #Medications #Pharmacology