62 results
Occult Causes of Non-Response to Vasopressors

vital disclaimer: the cognitive response to hypotension should not be reaching
Non-Response to Vasopressors ... reaching for a vasopressor ... hypotension is treatment ... despite substantial vasopressor ... #Differential #
Pharmacological Treatment of Hepatorenal Syndrome (HRS)

Midodrine - Alpha agonist incr blood pressure incr renal perfusion pressure
Pharmacological Treatment ... Hepatorenal Syndrome (HRS ... vasodilatation Vasopressin ... - V1 receptor agonist ... amzn.to/34t5DgJ #HRS
Hypotension in Anesthesiology - Differential Diagnosis and Management 

Initial checklist: 
 - Verify BP (e.g. surgeon
Anesthesiology - Differential ... compression) Initial treatment ... Administer inotropes / vasopressors ... epinephrine / vasopressin ... Anesthesiology #Differential
Vasopressors and Inotropes - Pharmacology Summary
Vasopressors
Phenylephrine (alpha-1)
 • Increases BP, SVR
 • Risk of reflex bradycardia
Vasopressors and ... Pharmacology Summary Vasopressors ... • Increases HR ... Dose dependent receptor ... min): increases HR
Second Generation Antipsychotics: Mechanisms and Side Effects
(Atypical Anti-Psychotics) - Examples: Clozapine, Olanzapine, Quetiapine, Risperidone, Zotepine, Paliperidone,
Note: Receptor binding ... efficacious, but also has ... considered 2nd line treatment ... • Dopamine D2 Receptor ... • Serotonin 2A Receptor
Hypocalcemia Laboratory Evaluation

Serum levels of PTH, phosphorus, 25-hydroxyvitamin D, and 1,25-dihydroxyvitamin D can help differentiate between
dihydroxyvitamin D can help differentiate ... Calcium-sensing receptor ... Hyperparathyroidism #Diagnosis #Endocrinology ... #Differential
Hepatorenal Syndrome - Diagnosis and Management Summary
Who gets HRS?
 • Decompensated cirrhosis
 • Typically with existing
infection Mainstay of treatment ... Mechanism: • Vasopressin ... • Acts on V1 receptors ... Hepatorenal #Syndrome #HRS ... Diagnosis #Management #treatment
Anaphylaxis: Treatments (Acute)
Additional Info:
 • IV steroids may be considered for prevention of late phase reactions.
Anaphylaxis: Treatments ... minimum of 4-6 hrs ... • H2 receptor ... to amplify H1 receptor ... non-sedating) PO q4-6hrs
Inherited Defects in Kidney Tubule Epithelial Cells

Renal glucosuria - Na+-dependent glucose cotransporter
Cystinuria - Amino acid transporter
Bartter
diabetes insipidus - Vasopressin ... -2 (V2) receptor ... antidiuresis - Increased vasopressin ... -2 (V2) receptor ... Nephrology #Diagnosis #Differential
Thrombotic Microangiopathy - TTP VS HUS

Big picture points : Often hard to differentiate the two entities,
Often hard to differentiate ... entities, but has ... this distinction has ... HUGE treatment ... and first-line treatment