13 results
Vasopressors and Inotropes - Pharmacology Summary
Vasopressors
Phenylephrine (alpha-1)
 • Increases BP, SVR
 • Risk of reflex bradycardia
Inotropes - Pharmacology ... • Higher doses cause ... Dose dependent receptor ... cAMP/cGMP • Causes ... #Inotropes #Pharmacology
Vasopressors Table 
Rough properties by Target Receptor, Heart Rate/Inotropy, Systemic Vascular Resistance, Cardiac Output, Blood Pressure,
properties by Target Receptor ... , Heart Rate/Inotropy ... Resistance, Main Uses ... Properties #Table #Pharmacology ... Management #Comparison #Inotropes
Diuretics and Agents Regulating Renal Excretion

Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide)
 • Glaucoma
 • Epilepsy
 • Altitude
Kidney stones caused ... Association class IV) Vasopressin ... (Vasopressin) ... bleeding disorders Vasopressin ... #Nephrology #Pharmacology
Diuretics - Pharmacology

Thiazides diuretics:
 • Inhibit Na+ Cl- cotransporter in distal tubule
 • Chlorothiazide, Chlorthalidone, Indapamide,
Diuretics - Pharmacology ... Mannitol, Urea Vasopressin ... receptor antagonists ... #Pharmacology # ... nephrology #conversion
Drugs associated with hypokalemia and hypomagnesemia

Hypokalemia
- Shift from extracellular fluid to intracellular fluid compartment
  -
compartment - b2-receptor ... - Anti-EGF receptors ... #Medications #differential ... #diagnosis #nephrology ... #Causes #hypomg
Common Medications Known to Prolong QTc
Antiarrhythmics - Amiodarone, sotalol, flecainide, quinidine, dronedarone, dofetilide
Vasopressors/inotropes - Epinephrine, norepinephrine,
dronedarone, dofetilide Vasopressors ... /inotropes - Epinephrine ... #Medications #Causes ... #differential # ... diagnosis #pharmacology
Antiarrhythmics - Vaughan Williams Classification:
CLASS 1 - Sodium Channel Blockers:
 • MOA: Block fast Na+ channels
Vaughan Williams Classification ... beta adrenergic receptors ... force (negative inotropy ... Vaughan #Williams #Pharmacology ... #Classification
Hyperkalemia - Differential Diagnosis Framework

PseudoHyperkalemia:
 • Lab error
 • Traumatic venipuncture
 • Hemolysis, thrombocytosis, leukocytosis
 •
Hyperkalemia - Differential ... • K sparing diuretics ... Beta adrenergic receptor ... #diagnosis #causes ... potassium #high #nephrology
Antiarrhythmics Pharmacology Summary
Cardiac Conduction Phases:
Phase 0 - Ventricular Depolarization:
 • Na+ channels open leading to a
Antiarrhythmics Pharmacology ... Vaughan Williams Classification ... beta adrenergic receptors ... force (negative inotropy ... #Classification
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis

The most common causes of hyperlactatemia are usually:
Lactic Acidosis - Differential ... administration, vasopressors ... , or inotropes ... Acidosis #Elevation #Differential ... #typea #typeb #classification