1430 results
Pharmacological Treatment of Hepatorenal Syndrome (HRS)

Midodrine - Alpha agonist incr blood pressure incr renal perfusion pressure
vasodilatation Vasopressin ... Terlipressin - Vasopressin ... edgarvlermamd - Nephrology ... HepatoRenal #Syndrome #Nephrology
Hyponatremia Diagnosis Algorithm
UOsm ≥ POsm - Vasopressin-Dependent
 • UNa < 20 mEq/L - Appropriate (↓ EABV)
UOsm ≥ POsm - Vasopressin-Dependent ... UOsm < POsm - Vasopressin-independent ... algorithm #causes #nephrology
Summary of Diuretic Agents 
Subclass, Drug, Mechanism of Action, Effects, Clinical Applications, Pharmacokinetics, Toxicities, Interaction
CARBONIC ANHYDRASE
• Mannitol VASOPRESSIN ... summary #table #nephrology
Diabetes Insipidus - Diagnosis Algorithm
Tests:
 • Osmolality, Urine AND/OR
 • Osmolality, Serum or Plasma AND
 •
• Administer vasopressin ... administration • Arginine Vasopressin ... Diagnosis #Algorithm #nephrology
Inherited Defects in Kidney Tubule Epithelial Cells

Renal glucosuria - Na+-dependent glucose cotransporter
Cystinuria - Amino acid transporter
Bartter
diabetes insipidus - Vasopressin ... antidiuresis - Increased vasopressin ... Defects #Kidney #Nephrology
Hepatorenal Syndrome Treatment
Volume expansion: 
 • Albumin (typical dose = 1g/kg on day 1 +/- day
Norepinephrine, vasopressin ... management #HRS #nephrology
REBEL Review 4 & 5: Paralytic & Vasopressor Dosing 

Paralytic Agents:
 - Succinylcholine (Depolarizing Agent)
5: Paralytic & Vasopressor ... Rocuronium Vasopressors ... Phenylephrine - Vasopressin ... #vasopressors
Tailoring Vasopressors to a Patient's Physiology

Overall, norepinephrine, epinephrine, and vasopressin are all supported by evidence as
Tailoring Vasopressors ... epinephrine, and vasopressin ... potential first-line vasopressors ... #CriticalCare #Vasopressor
Hyponatremia Differential Diagnosis Algorithm in Cancer
UOsm ≥ 100 mOsm/kg = Urine is inappropriately concentrated for hypotonic
hypotonic plasma = Vasopressin-dependent ... mEq/l = ↓EABV = Vasopressin ... ↑ or N EABV = Vasopressin ... Cancer #algorithm #nephrology
Management of SIADH
Treat underlying cause:
 • Causes can include pain, primary lung pathology, post-operative phenomenon, medications,
bolus of 0.9% NS Vasopressor ... #hyponatremia #nephrology