14 results
Veltassa (Patiromer) 
MECHANISM: Potassium Binder 
INDICATION: Treatment of Hyperkalemia 
FORMULATION: Powder for oral suspension 
DOSING: 8.4
Veltassa (Patiromer ... least 3 hours Veltassa ... Veltassa can be ... /ambcarerx #Veltassa ... #KBinder #Hyperkalemia
Parathyroid Hormone (PTH) Effect in Calcium and Phosphorus
Calcium - Net Effect Hypercalcemia:
   ↑ intestinal
in Calcium and Phosphorus ... tubular reabsorption Phosphorus ... parathormone #Calcium #Phosphorus ... #pathophysiology
Pathophysiology of Tumor Lysis Syndrome (TLS)
Tumor Cell Lysis
-> Release of DNA
 • Purines -> Hypoxanthine /
Pathophysiology ... excretion) • Phosphorus ... Syndrome #TLS #Pathophysiology
Potassium Binders for Management of Hyperkalemia
 • SPS - Sodium polystyrene sulfonate
 • Patiromer (veltassa)
 •
Potassium Binders ... • Patiromer (veltassa ... cyclosilicate #Potassium #Binders
Initial treatment of renal bone disease and cinacalcet for secondary hyperparathyroidism
Phosphate binders reduce hyperphosphataemia and hyperparathyroidism.
hyperparathyroidism Phosphate binders ... Calcium-containing phosphate binders ... #Pharmacology #Pathophysiology
Phosphate Binders
#Pharmacology #Nephro #Phosphate #Phosphorus #Binders #Comparison #Table #Disadvantages #SideEffects
Phosphate Binders ... Nephro #Phosphate #Phosphorus ... #Binders #Comparison
Hypophosphatemia - Differential Diagnosis Algorithm
Appropriately Low Kidney Phosphate Excretion:
 • Decreased GI Absorption: Chronic Diarrhea, Antacids,
Antacids, Phosphate Binders ... Algorithm #nephrology #phosphorus
Workup for Hypophosphatemia - Differential Diagnosis Framework
Rule out spurious hypophosphatemia: paraproteinemia, acute leukemia
Measure Urine Fractional Excretion
absorption (Antacids, Phosphorus ... binders, Niacin
Potassium-Binding Agents to Treat Hyperkalemia
Sodium zirconium cyclosilicate (Lokelma):
 • Mechanism: Preferentially captures K in exchange for
hypokalemia Patiromer (Veltassa ... table #comparison #binders
Hypophosphatemia and Hypoxia - Pathophysiology

↓ Phosphate leads to ↓ red cell 2,3-DPG and a  reduction
and Hypoxia - Pathophysiology ... change in serum phosphorus ... ↓ phosphorus ... condition of renal phosphorus ... respiratory #hypoxia #pathophysiology