17 results
BRASH Syndrome

B - Bradycardia
R - Renal failure
A - AV nodal blockade
S - Shock
H - Hyperkalemia

Typical ECG
BRASH Syndrome ... blockade S - Shock ... Hyperkalemia Typical ECG ... #diagnosis #management ... #pathophysiology
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... Triggers: ATRA treatment ... Pathophysiology ... Prednisone 5mg/kg ... #management #hematology
Acquired von Willebrand Syndrome - Diagnosis and Management
 • Autoantibodies to vWF: Lymphoproliferative disorders (e.g. lymphoma,
von Willebrand Syndrome ... Diagnosis and Management ... Lymphoproliferative disorders (e.g ... Myeloproliferative disorders (e.g ... #treatment #hematology
Shock - Differential Diagnosis Framework
 - MAP <65. SBP <90, drop in SBP > 40
 -
Abdominal compartment syndrome ... Treatment Goals ... ) UOP > 0.5 cc/kg ... Differential #Diagnosis #criticalcare ... #management
Shock - Diagnosis and Management Summary
 • Hypotension: SBP<90, SBP drop >40, MAP<65 (Normotension, HTN possible
and Management ... telemetry, 12-Lead EKG ... #Diagnosis #Management ... #Summary #criticalcare ... #treatment #workup
Pancreatitis management checklist 
Evaluation to guide etiology & management 
 - RUQ ultrasound 
 - Calcium
as for septic shock ... (e.g. moderate ... resuscitation (e.g ... choledolithiasis (e.g ... #CriticalCare
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... : • Pathophysiology ... unless worrisome EKG ... TLS #diagnosis #management ... #hematology
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Demyelinating Syndrome ... Disease, PRES Pathophysiology ... Lumbar Puncture, EEG ... cerebritis #diagnosis #management ... #treatment
Tumor Lysis Syndrome
An acute, life-threatening condition that appears within 7 days of starting cytotoxic therapies in
Tumor Lysis Syndrome ... (both ALL and AML ... malignancies Treatments ... with Ca only if EKG ... TLS #oncology #management
Stiff Person Syndrome (SPS) - Diagnosis and Management Summary

Epidemiology:
 • Prevalence: 1-2 cases per million -
Diagnosis and Management ... Pathophysiology ... unit activity on EMG ... of diazepam • EMG ... TPO, TTG, etc EMG