17 results
Diagnosis of Cryoglobulinemia Vasculitis

1) Presence of cryoglobulin 
Circulating immunoglobulins that precipitate with cold temperature and dissolve
Vasculitis 1 ... (type l) : Vascular ... Hyperviscosity syndrome ... and Ill) • Vascular ... #Rheumatology #
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
platelet disorders, vascular ... Etiology: • Vascular ... Disruptions in vascular ... Streptococcus pneumoniae Vascular ... Differential #Diagnosis #hematology
Cryoglobulinemia Summary

Cryoglobulins:
 • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
Vascular Sludging ... Hyperviscosity Syndrome ... Syndrome: • Clinical ... syndrome in 80% ... classification #rheumatology
Petechiae/Purpura - Diagnostic Algorithm. Pathophysiology: 1) Represent the passage of erythrocytes from the intravascular to extravascular
Purpura - Diagnostic Algorithm ... disruption of vascular ... trauma, infection, vasculitis ... #Diagnosis #Dermatology ... #Rash #Petechiae
Causes of Bleeding / Bruising - Differential Diagnosis Algorithm
Thrombocytopenia - Quantitative Defect
 • Decreased Production
 •
Differential Diagnosis Algorithm ... Renal Disease Vascular ... TeIangiectasia Vascular ... • Steroids • Vasculitis ... #Causes #Hematology
Skin Ulcers by Etiology - Differential Diagnosis Algorithm
Physical:
 • Trauma
 • Pressure
 • Radiation
Vascular:
 • Arterial
Differential Diagnosis Algorithm ... • Radiation Vascular ... insufficiency • Vasculitis ... Thalessemia • Cryoglobulinemia ... ulcerative #skinrash #dermatology
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA)

Skin involvement in granulomatosis with polyangiitis (GPA) is common and
Maculopapular rash ... purpura • Mixed cryoglobulinemia ... • Goodpasture syndrome ... #rash #diagnosis ... #rheumatology
Causes of Petechial Rash - Differential Diagnosis Algorithm

Pinpoint areas (less than 2 mm) of hemorrhage, which
Differential Diagnosis Algorithm ... Disruptions in vascular ... Infection - Vasculitis ... - Autoimmune Vasculitis ... #Causes #dermatology
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
ANCA +MPO) • Cryoglobulinemic ... and bullous or vesicular ... mucositis - Rash ... Low levels mixed cryoglobulinemia ... differential #diagnosis #rheumatology
Paraproteinemias

Entities That Can Feature A Monoclonal Protein/M Component:
• MM
• WM
• MGUS
• MGCS
• MGRS
• Splenic Marginal Zone
Immunotactoid GN & Cryoglobulinemic ... (Cryoglobulinemic ... Vasculitis) Autoantibodies ... (Thrombosis in vascular ... Paraproteinemias #Hematology