13 results
Criss-Cross Gait on Physical Exam 

Seen in Glucose Transporter type 1 Deficiency Syndrome

#CrissCross #Criss #Cross #Gait
Criss-Cross Gait ... Syndrome #CrissCross ... PhysicalExam #clinical #video ... #neurology #GLUT1 ... #deficiency
Differential diagnosis of schistocytes / fragmentation hemolysis:
 • Thrombotic microangiopathies (TMA)
    - TTP
Differential diagnosis ... syndrome (ST-HUS ... • Severe B12 deficiency ... anemia" • HELLP ... #diagnosis #hematology
Criss-Cross Gait on Physical Exam 

Seen in Glucose Transporter type 1 Deficiency Syndrome

#CrissCross #Gait #PhysicalExam #clinical
Criss-Cross Gait ... Syndrome #CrissCross ... #clinical #video ... #neurology #GLUT1 ... #deficiency
Criss-Cross Gait on Physical Exam 

Seen in Glucose Transporter type 1 Deficiency Syndrome

#CrissCross #Gait #PhysicalExam #clinical
Criss-Cross Gait ... Syndrome #CrissCross ... #clinical #video ... #neurology #GLUT1 ... #deficiency
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 • Mechanical Trauma (Microangiopathic hemolytic anemia):
anemia): ... uremic syndrome ... G6PD deficiency) ... Extravascular #Causes #differential ... #anemia
Red Blood Cell (RBC) Morphology Atlas
 • Microcytic - Iron-deficiency anemia, Thalassemia, Sideroblastic anemia, Lead poisoning
Myelodysplastic syndrome ... spherocytosis, Hemolytic ... uremic syndrome ... key #diagnosis #differential ... #hematology
Pancytopenia - Differential Diagnosis

Congenital Diseases:
• GATA2 deficiency
• Fanconi’s anemia
• Wiskott-Aldrich syndrome
• Ribosomopathy or telomeropathy

Cancer:
• Leukemia
• Lymphoma

Inflammatory
Pancytopenia - Differential ... • Fanconi’s anemia ... Wiskott-Aldrich syndrome ... Antibody-mediated hemolysis ... #Diagnosis #Hematology
Iron Deficiency Anemia - Differential Diagnosis Algorithm

Labs: Ferritin, iron, transferrin, TIBC, TSAT, sTfR

 • Blood loss:
Anemia - Differential ... extravascular) hemolysis ... Gastrectomy, WHDA syndrome ... #Anemia #Differential ... Algorithm #ferritin #hematology
Causes of Thrombocytosis - Differential Diagnosis
Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis):
 • Acute infection
 • Solid organ
Thrombocytosis - Differential ... malignancies • Anemia ... specifically: iron deficiency ... , hemolysis, hemorrhage ... Myelodysplastic syndrome
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
Platelet Count - Differential ... blood loss, Acute hemolysis ... , deficiency anemia ... Kawasaki, Nephrotic syndrome ... Thrombocytosis #Platelets #Differential