10 results
Renal Tubular Acidosis (RTA) Diagnosis and Management
 • Distal (type 1) RTA
 • Proximal (type 2)
Renal Tubular Acidosis ... Management • Distal ... type 2) RTA • Hyperkalemic ... Diagnosis #Management #nephrology ... #table
Gitelman Syndrome Pathophysiology
Gitelman Syndrome is a rare autosomal recessive salt-losing tubulopathy with a prevalence of 1-
Gitelman Syndrome ... Pathophysiology Gitelman ... tubule. ↑ Nacl ... H+ secretion → Hypokalemia ... Pathophysiology #nephrology
Inherited Defects in Kidney Tubule Epithelial Cells

Renal glucosuria - Na+-dependent glucose cotransporter
Cystinuria - Amino acid transporter
Bartter
Defects in Kidney Tubule ... ascending limb Gitelman ... cotransporter in distal ... Defects #Kidney #Nephrology ... #Differential #Table
Hypokalemia - Differential Diagnosis Algorithm
Extra-renal Losses:
 • Normal Acid-Base: Low intake
 • Metabolic acidosis: Gl tract
Hypokalemia - Differential ... Diagnosis Algorithm ... : Proximal and distal ... Bartter syndrome, Gitelman ... potassium #low #nephrology
Renal Tubular Acidosis - Differential Diagnosis Algorithm
Decreased Serum K, Urine pH < 5.5 - Proximal RTA
Decreased
Differential Diagnosis Algorithm ... - Hypokalemic distal ... Increased Serum K = Hyperkalemic ... Differential #Diagnosis #Algorithm ... #nephrology
Causes of Hypokalemia - Differential Diagnosis Algorithm
Defining the cause of hypokalemia starts by measuring urinary K
Differential Diagnosis Algorithm ... • Renal tubular ... Bartter's syndrome, Gitelman's ... differential #diagnosis #algorithm ... #causes #nephrology
Gitelman Syndrome Overview

What?
• Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter
• Gitelman's syndrome
Gitelman Syndrome ... of cells on the distal ... convoluted tubule ... syndrome, Renal tubular ... Syndrome #diagnosis #nephrology
Hypokalemia Evaluation Algorithm

Before evaluating hypokalemia, life threatening complications such as arrhythmias and paralysis should be looked
Algorithm Before ... Bartter syndrome, Gitelman ... Proximal RTA, Distal ... #diagnosis #Algorithm ... differential #potassium #nephrology
Algorithm for patients with hypokalemia on the basis of the potassium-to-creatinine ratio in the urine
Urine K+
Algorithm for patients ... with hypokalemia ... Proximal RTA • Distal ... Bartter syndrome, Gitelman ... #diagnosis #nephrology
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary

Causes of Rhabdomyolysis:
 • Trauma:
	- Immobilization
	- Crush injury
	- Compartment
- Infection - Viral ... formation: Renal tubular ... nephrotoxicity to kidney tubular ... per day until stable ... causes #treatment #nephrology