13 results
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm
Reactive:
 - Systemic Inflammatory
     •
- Differential Diagnosis ... Algorithm Reactive ... (Pancytopenia, WBC ... #Algorithm #Causes ... #Hematology #Oncology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic Syndrome ... Summary myelo ( ... transformation to acute leukemia ... Myelodysplastic #Syndrome ... #hematology #oncology
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
- Summary Cancer ... Lymphadenopathy • Fevers ... Lymphocytosis on CBC ... #diagnosis #workup ... #oncology #hematology
Chronic Lymphocytic Leukemia (CLL) - Summary
Overview: 
 • Most common leukemia in adults
 • Disorder of
(CLL) - Summary ... ) B symptoms → fevers ... #oncology #hematology ... #hemeonc #diagnosis ... #management
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
Headaches, bone pain, fever ... develop leukostasis syndrome ... • Tumor lysis syndrome ... #Hematology #Oncology ... #Diagnosis
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
virus (EBV) • Leukemia ... • ↓ WBC • ↓ ... Aplastic #Anemia #oncology ... #hematology #diagnosis ... #management
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... if high risk if WBC ... Subacute-Acute: • Common: fever ... #management #hematology ... #oncology
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
blasts and high WBC ... - 80% have fever ... • Lab values: WBC ... #TLS #diagnosis ... #management #hematology
Polycythemia Vera (PV) - Diagnosis and Management Summary
Diagnostic Criteria:
 • Elevated hemoglobin and/or hematocrit AND
 •
and Management ... Summary Diagnostic ... • Treatment algorithms ... #Management #Summary ... #treatment #hematology
Hodgkin's Lymphoma Overview

Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
• Dyspnea • Fever ... platelets - WBC ... lymph node biopsy (diagnostic ... classification #hematology ... #oncology #management