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Dacrocytes (tear drop cells) 
Other poikilocytes resemble a pear or teardrop. The narrow, tapered end
may be
each of the above photos ... thalassemia, and some hemolytic ... anemias. ... #Clinical #Path ... #BloodSmear #Blood
SLICC SLE Diagnostic Criteria - Systemic Lupus Erythematosus
Clinical and Immunologic Criteria

CLINICAL CRITERIA
 - ACUTE CUTANEOUS LUPUS
Erythematosus Clinical ... Immunologic Criteria CLINICAL ... ANEMIA - LEUKOPENIA ... #Rheumatology # ... SLE #Lupus #Erythematosus
Codocytes (Target cells) - Two target cells are seen in the left photo and one in
seen in the left photo ... associated with hemolytic ... anemias, especially ... #Clinical #Path ... #BloodSmear #Blood
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Clinical Features ... of Systemic Lupus ... Glomerulonephritis Myositis(5%) Blood ... (75%): Anemia ( ... SLE #systemic #erythematosus
Howell-Jolly Body - On these Wright-stained peripheral blood smears the small dark spheres within red cells
Wright-stained peripheral blood ... cells in the right photo ... can be found in hemolytic ... #Clinical #Path ... #BloodSmear #Blood
Schistocytes - The arrows point to schistocytes which are fragmented red blood cells. Also called schizocytes,
fragmented red blood ... In the right photo ... anemias, especially ... anemia in which ... #Clinical #Path
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Suspect: Clinical ... Malignancy (e.g. hematologic ... vein thrombosis Hematologic ... lymphopenia, low PLT • Anemia ... titers > 1:80 • CBC
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Viral Infection Clinical ... Immunoglobulin M (IgM) • Blood ... smear - RBC agglutination ... sensitize red blood ... #anemia #hematology
Spherocytes - The arrow points to one of many spherocytes in this photo. The cells have
spherocytes in this photo ... spherocytosis and hemolytic ... anemias. ... #Clinical #Path ... #BloodSmear #Blood
Paraproteinemias

Entities That Can Feature A Monoclonal Protein/M Component:
• MM
• WM
• MGUS
• MGCS
• MGRS
• Splenic Marginal Zone
MGCS • MGRS • Splenic ... • Coombs (-) hemolytic ... anemia due to cold ... IgG • Lupus anticoagulant ... Paraproteinemias #Hematology