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Summary Table of Paraneoplastic Syndromes

#Diagnosis #Oncology #Paraneoplastic #Syndromes #Table
Summary Table of ... Paraneoplastic Syndromes ... #Diagnosis #Oncology ... Paraneoplastic #Syndromes ... #Table
Gastric Neuroendocrine Tumor (NET) Types
Type 1 - Chronic atrophic gastritis and pernicious anaemia
Type 2 - Zollinger
and pernicious anaemia ... Zollinger Ellison syndrome ... Classification #oncology ... #comparison #table
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Constitutional Syndromes ... Constitutional Syndromes ... Pancytopenia: • ↓ RBC ... • ↓ WBC • ↓ ... #oncology #hematology
Red Blood Cell (RBC) Morphology Atlas
 • Microcytic - Iron-deficiency anemia, Thalassemia, Sideroblastic anemia, Lead poisoning
Red Blood Cell (RBC ... Iron-deficiency anemia ... Myelodysplastic syndrome ... Hemolytic uremic syndrome ... coagulopathy (DIC) #RBC
Oncologic Emergencies - Differential Diagnosis Framework

HEMATOLOGIC ONCOLOGIC EMERGENCIES:
Hyperviscosity Syndrome:
 • Spontaneous bleeding
 • Shortness of breath
Oncologic Emergencies ... Hyperviscosity Syndrome ... Leukostasis: • WBC ... Superior Vena Cava Syndrome ... : Tumor Lysis Syndrome
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Normal Blood Smear
 •
Causes of Anemia ... Neutrophils - Low RBC ... • Pernicious Anemia ... Myelodysplastic Syndromes ... Cells, Normal WBCs
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic Syndrome ... cytopenias (usually anemia ... Myelodysplastic #Syndrome ... treatment #hematology #oncology
Drugs Implicated in Hemolytic Anemia
 • Hapten (Drug binding to RBC membrane): Penicillin, Cephalosporin, Tetracycline, Tolbutamide,
Implicated in Hemolytic Anemia ... Drug binding to RBC ... complex binds to RBC ... medications #Hemolytic #Anemia ... #pharmacology #table
Micronutrient Deficiencies After Gastric Bypass
Fat-Soluble Vitamins:
 • Vitamin A - Night/complete blindness, xeropthalmia (pathologic dryness of
ataxia), Korsakoff syndrome ... Folate - Macrocytic anemia ... B12 - Macrocytic anemia ... Minerals: • Iron - Anemia ... vitamin #nutrition #table
Blood Disorders - Markers and Differential Diagnosis Algorithm 
Acute
 • Myloid (AML) - CD13, CD33, CD34,
Pelger-Huet, Macrocytic anemia ... o CML - bcr-able ... (+) ↑ WBC ... o Other bcr-able