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diagnosis hematology nephrology rheumatology differential physicalexam video algorithm oncology bppv instructions maneuver positional vertigo causes disease infectiousdiseases pharmacology workup pathophysiology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Clinical Presentation ... Pancytopenia: • ↓ RBC ... • ↓ WBC • ↓ ... Treatment: ... hematology #diagnosis #management
Warm Antibody Autoimmune Hemolytic Anemia 1) DIAGNOSE AIHA • Anemia: macrocytic > normocytic, ↑ reticulocytes •
Autoimmune Hemolytic Anemia ... DIAGNOSE AIHA • Anemia ... ↑ LDH • Anti-RBC ... #diagnosis #management ... #treatment #rheumatology
Korsakoff Syndrome Clinical Findings: • Confabulation: Usually initial phase of the disease • Anterograde amnesia: Memory impairment
Korsakoff Syndrome ... Clinical Findings ... • Anterograde amnesia ... Encephalopathy Treatment ... #neurology #diagnosis
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic Syndrome ... cytopenias (usually anemia ... only curative treatment ... Myelodysplastic #Syndrome ... #treatment #hematology
Pharmacological Treatment of Hepatorenal Syndrome (HRS) Midodrine - Alpha agonist incr blood pressure incr renal perfusion pressure
Pharmacological Treatment ... of Hepatorenal Syndrome ... #HepatoRenal #Syndrome ... #Nephrology #Management ... #Medications #Treatment
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
blasts and high WBC ... • Lab values: WBC ... organ damage • Treatment ... Low calcium • Treatment ... TLS #diagnosis #management
Posterior Reversible Encephalopathy Syndrome (PRES) - Treatment Blood pressure control: • Aim for 10-25% BP reduction within
Encephalopathy Syndrome ... (PRES) - Treatment ... Encephalopathy #Syndrome ... #Treatment #Management ... #Neurology
Guillain-Barre Syndrome - Summary Acute AIDP that presents with rapidly progressive flaccid weakness Epidemiology: • 1-2 cases/100,000 per
meningococcal, H1N1) Clinical ... Guillain-Barre Clinical ... - NORMAL CSF WBC ... #diagnosis #management ... #treatment #neurology
Hypereosinophilia and Hypereosinophilic Syndrome • Secondary Hypereosinophilic Syndrome • Clinically Relevant HES Variants • When to
Hypereosinophilic Syndrome ... Hypereosinophilic Syndrome ... • Clinically ... Diagnosis and Treatment ... eosinophils #diagnosis #management
Hepatorenal Syndrome Treatment Volume expansion: • Albumin (typical dose = 1g/kg on day 1 +/- day
Hepatorenal Syndrome ... Treatment Volume ... #Hepatorenal #Syndrome ... #Treatment #management ... #HRS #nephrology
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