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differential oncology elevatedmcv macrocytosis approach atlas classification cll leukemia lymphocytic management mcv mds microcytic morphologic morphology myelodysplasia myelodysplastic nomenclature normocytic
Causes of Anemia with Normal Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Decreased WBCs - Decreased/NormaI
Causes of Anemia ... • Marrow Aplasia ... Macrocytes, Normal ... #Algorithm #Causes ... #Hematology
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Normal Blood Smear •
Causes of Anemia ... Algorithm Normal ... WBCs - Normal ... #Algorithm #Causes ... #Hematology
Red Blood Cell (RBC) Morphology Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
Microcytic RBC: ... , Chronic disease ... (sometimes) Macrocytic ... #Red #BloodCell ... #hematology #microscopy
Diagnostic Framework for Anemia (Morphological Approach - MCV) Low MCV - <80fL - "Microcytic" • Iron deficiency
Diagnostic Framework ... some patients) Normal ... blood loss, Anemia ... Myelodysplastic syndrome ... #causes #hematology
Overall Approach to Anemia - Differential Diagnosis Algorithm Blood Loss • Acute Bleed - Normocytic / Normochromic
Algorithm Blood ... Deficiency • Aplastic ... of Chronic Disease ... #Algorithm #Causes ... #Hematology
Causes of Anemia with Low Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Decreased Heme Synthesis or
Causes of Anemia ... : Chronic Blood ... #Microcytic #Anemia ... #Algorithm #Causes ... #Hematology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Aplastic Anemia ... • Aplastic anemia ... Anemia Clinical ... • ↓ WBC • ↓ ... #hematology #diagnosis
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
common cytopenia: Macrocytic ... • Anemia • Aplastic ... Marrow Failure • Chronic ... Myeloproliferative Disease ... #diagnosis #hematology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Orange or Hep C Clinical ... cells can indicate disease ... • Neutropenia, anemia ... Pure red cell aplasia ... workup #oncology #hematology
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