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diagnosis oncology anemia differential management algorithm causes approach calculation cirrhosis cll coagulation dic disseminated hepatopulmonary hodgkins hps index intravascular leukemia
Overall Approach to Anemia - Differential Diagnosis Algorithm Blood Loss • Acute Bleed - Normocytic / Normochromic
Diagnosis Algorithm Blood ... Deficiency • Aplastic ... Disease • Marrow ... Non-lmmune #Anemia #Classification ... Algorithm #Causes #Hematology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
→ Refer to hematology ... for workup, including ... : Acute blood loss ... • Infections: Chronic ... Diagnosis #Algorithm #hematology
Reticulocyte Production Index = (Retic %) x (Hct / 45) / Maturation Factor The maturation factor is
the peripheral blood ... • Anemia of chronic ... kidney disease, ... marrow failure: Aplastic ... Production #Index #hematology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Pancytopenia: • ↓ RBC ... • ↓ WBC • ↓ ... anemia Treatment ... result from low blood ... Anemia #oncology #hematology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
cells can indicate disease ... Lymphocytosis: Absolute blood ... Pure red cell aplasia ... microglobulin Treatment ... #oncology #hematology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
formed or don’t work ... Causes • Anemia • Aplastic ... Marrow Failure • Chronic ... Myeloproliferative Disease ... #diagnosis #hematology
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
ABO incompatible blood ... protein C and S Pathophysiology ... • Severe Liver Disease ... hydration • RBC ... #management #hematology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Hodgkin Lymphoma Workup ... platelets - WBC ... number of sites of disease ... Hodgkin Lymphoma Treatment ... #hematology #oncology
Hepatopulmonary Syndrome - Illness Script HPS is a pulmonary disorder of chronic liver disease characterized by a
pulmonary disorder of chronic ... triad of: 1) chronic ... abnormalities PATHOPHYSIOLOGY ... shunting causes mixed blood ... cirrhosis #diagnosis #hepatology
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