17 results
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 • Mechanical Trauma (Microangiopathic hemolytic anemia):
) - HELLP syndrome ... uremic syndrome ... lymphoproliferative disorders ... #differential # ... diagnosis #hematology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
→ Refer to hematology ... : Acute blood loss ... , Acute hemolysis ... Kawasaki, Nephrotic syndrome ... #hematology
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Normal Blood Smear
 •
Causes of Anemia ... Normal Blood Smear ... Myelodysplastic Syndromes ... Cells, Normal WBCs ... #Causes #Hematology
Hemolysis - Differential Diagnosis Framework

1) Environment
  - Fragmentation
  - MAHA: TTP, HUS, DIC, HELLP
Hemolysis - Differential ... Drug-associated, PCH, Evans Syndrome ... ) - Infections ... - Peripheral Blood ... Diagnosis #hematology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
Diagnosis and Workup ... procedures - Infection ... changes), high MCV anemia ... Diagnosis #Causes ... #Workup #hematology
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
anemia - Splenomegaly ... Kasabach-Merritt syndrome ... Gardner-Diamond syndrome ... #Diagnosis #hematology ... #rheumatology #
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Cold Agglutinin Syndrome ... Diagnosis: • hemolytic ... younger pts) Differential ... #hemolytic #anemia ... #hematology #diagnosis
Causes of Neutropenia - Differential Diagnosis
Neonate:
 - Infection - by far the most common cause
 -
neutropenia, Kostmann syndrome ... Chediak-Higashi syndrome ... including white blood ... #diagnosis #causes ... #hematology
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
Myelodysplastic Syndromes ... caused by blood ... Myeloproliferative Disease ... differential • ... #diagnosis #hematology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Syndrome (MAS) ... Periodic fever syndromes ... #Syndrome #Diagnosis ... #Management #Hematology ... #Rheumatology