WBC blood treatment hematology disease syndrome infectiousdiseases rheumatology workup management classification hepatology approach hlh

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Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?

Approach to Thrombocytosis ... → Refer to hematology ... for workup, including ... : Acute blood loss ... Diagnosis #Algorithm #hematology

Overall Approach to Anemia - Differential Diagnosis Algorithm

Blood Loss
• Acute Bleed - Normocytic / Normochromic

Overall Approach ... Diagnosis Algorithm Blood ... Anemia of Chronic Disease ... Non-lmmune #Anemia #Classification ... Algorithm #Causes #Hematology

Consensus Indications for Irradiated RBC Transfusions:

Cellular blood components are irradiated for the prevention of TA-GVHD. Transfused

for Irradiated RBC ... Transfusions: Cellular blood ... disorders (DiGeorge Syndrome ... #Indications #Hematology ... #BloodBank #Management

Hemophagocytic Lymphohistiocytosis (HLH) Treatment
Primary HLH:
- HLH-94 Protocol
• Dexamethasone

: • Approach varies ... or autoimmune disease ... for refractory disease ... #Treatment #management ... #hematology

Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to

Overwhelming clinical syndrome ... age, however the disease ... • Bicytopenia Treatment ... Lymphohistiocytosis #diagnosis #management ... #treatment #hematology

Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of

lymphohistiocytosis (HLH ... • HLH Labs: ... Treatment: • Corticosteroids ... #Diagnosis #Management ... #Hematology #Rheumatology

Hodgkin's Lymphoma Overview

Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It

Hodgkin Lymphoma Workup ... platelets - WBC ... number of sites of disease ... #hematology #oncology ... #management

Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years

What?
• Aplastic anemia

• ↓ WBC • ↓ ... aplastic anemia Treatment ... result from low blood ... Anemia #oncology #hematology ... #diagnosis #management

Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly

formed or don’t work ... Myeloproliferative Disease ... factor (GCSF) treatments ... Workup: • Complete ... #diagnosis #hematology

Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
• Lymphocytes accumulate in large numbers

cells can indicate disease ... Lymphocytosis: Absolute blood ... microglobulin Treatment ... Leukemia #diagnosis #workup ... #oncology #hematology

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