WBC diagnosis differential hematology clinical hepatology pathophysiology syndrome rheumatology classification pancytopenia workup cirrhosis management biliary primary

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14 results

Pancytopenia - Workup and Differential Diagnosis Algorithm
Consumption Disorders
1. Autoimmune Mediated Pancytopenia
2. Splenic Sequestration
Peripheral Destruction

Pancytopenia - Workup ... and Differential ... Primary hematological ... #Workup #Differential ... #Hematology

Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
• Female:Male 9:1
• Common European descent
• Age:

Primary Biliary ... Cirrhosis (PBC) ... #Biliary #Cirrhosis ... #diagnosis #workup ... #hepatology

Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
- Prior platelet count, family

Platelet Disorders - Differential ... Diagnosis and Workup ... unclear, or if a primary ... ITP, unexplained pancytopenia ... #Workup #hematology

Portal Hypertension - Differential Diagnosis
Portal Pressure = the pressure difference between the pressure in the portal

Diagnosis Portal ... >10 mmHg - clinically ... pregnancy • Primary ... biliary cirrhosis ... #hepatology

Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years

What?
• Aplastic anemia

bone marrow + pancytopenia ... Aplastic Anemia Clinical ... ↓ WBC • ↓ PLT ... Anemia #oncology #hematology ... #diagnosis #management

Differentiation Syndrome in APML
Epidemiology:
• Incidence: common in APL (2-48% depending on the study)
• Triggers:

Differentiation Syndrome ... ATRA treatment Pathophysiology ... if high risk if WBC ... initiation • Differential ... #management #hematology

Antinuclear Antibodies (ANA)
ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like

likely it will be clinically ... Autoimmune Hepatitis, Primary ... Biliary Cirrhosis ... ANA #patterns #rheumatology ... #diagnosis #differential

Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
1. Cold Agglutinins (CAD)
2. Donath-Landsteiner

15% of AIHA Primary ... Cold Agglutinin Syndrome ... Viral Infection Clinical ... younger pts) Differential ... hemolytic #anemia #hematology

Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
• Bleeding
• Recent history

protein C and S Pathophysiology ... organ damage Clinical ... Treatment: • Treat primary ... #Coagulation #diagnosis ... #hematology

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