WBC diagnosis hematology symptoms causes dermatology signs management hepatology monoclonal mgus multiplemyeloma workup aplastic algorithm differential chronic eosinophilia

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Suggested algorithm for follow-up of monoclonal gammopathy of undetermined significance (MGUS)
Mayo Clinic Risk Stratification Model. CBC,

Eosinophil Disorders Testing Algorithm
INDICATIONS FOR TESTING:
• Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or

Testing Algorithm ... (common causes ... organ-specific signs ... #Differential # ... diagnosis #hematology

Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm
Reactive:
- Systemic Inflammatory
•

Diagnosis Algorithm ... Age > 50 • Chronic ... Lymphocytes) - Monoclonal ... #Diagnosis #Algorithm ... #Causes #Hematology

Causes of Anemia with Normal Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Decreased WBCs
- Decreased/NormaI

Diagnosis Algorithm ... • Marrow Aplasia ... RA, SLE, PRV, Chronic ... #Diagnosis #Algorithm ... #Causes #Hematology

Overall Approach to Anemia - Differential Diagnosis Algorithm

Blood Loss
• Acute Bleed - Normocytic / Normochromic

Diagnosis Algorithm ... RBCs on Smear • Chronic ... Deficiency • Aplastic ... #Diagnosis #Algorithm ... #Causes #Hematology

Causes of Polycythemia (Erythrocytosis) - Differential Diagnosis Algorithm
Relative - Normal RBC Mass / Decreased Plasma Volume

Diagnosis Algorithm ... Relative - Normal RBC ... Chest Symptoms ... #Diagnosis #Algorithm ... #Causes #Hematology

Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years

What?
• Aplastic anemia

and petechiae Causes ... - Hepatitis, eosinophilic ... • Improve the symptoms ... Anemia #oncology #hematology ... #diagnosis #management

$Polycythemia - Differential Diagnosis Algorithm Polycythemia itself isn’t a diagnosis. Like many things, it is a condition$

Diagnosis Algorithm ... Better call hematology ... normal/high - Chronic ... #Diagnosis #Algorithm ... #workup #hematology

Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
• Lymphocytes accumulate in large numbers

with no early symptoms ... Physical Exam/Signs ... Pure red cell aplasia ... #workup #oncology ... #hematology

Elevated Globulin - Protein Gap (Total Protein - Albumin > 4)

Work-up of an Elevated Globulin Gap:
•

Albumin > 4) Work-up ... Causes of Monoclonal ... Gammopathy Include: • MGUS ... gastric tumors • Hematology ... #diagnosis #hematology

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