35 results
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Differential Diagnosis ... lymphopenia, low PLT • Anemia ... : • Symptoms limited ... 1, SCL-70, RNP antibodies ... #Diagnosis #Rheumatology
BEE Syndromes - Immune-mediated conditions affecting the brain, eye, and ear

Visual or auditory symptoms in conjunction
Inflammatory causes ... • Systemic lupus ... erythematosus ... vasculitides • ... #neurology #inflammatory
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Normal Blood Smear
 •
Causes of Anemia ... Myelodysplastic Syndromes ... Cells, Normal WBCs ... • Rule out B12 and ... #Hematology
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies)
 • Systemic lupus erythematosus
   1. Anti-dsDNA
) • Systemic lupus ... erythematosus ... • Sjögren syndrome ... Vasculitis: • ... #diagnosis #rheumatology
Systemic Lupus Erythematosus - Diagnosis
Manifestations:
 - Arthritis 69%
 - Malar rash 40%
 - Fever 36%
 -
Systemic Lupus Erythematosus ... - Hemolytic anemia ... : - ANA 95-100% ... and Lupus Mimickers ... #signs #symptoms
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Erythematosus ( ... Demyelinating Syndrome ... Disease, PRES Pathophysiology ... autoantibodies that will cause ... #SLE #CNS #neurology
Antinuclear Antibodies (ANA)
ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
Antinuclear Antibodies ... context of other symptoms ... SLE), Sjogren's Syndrome ... Arthritis, Sjögren Syndrome ... #rheumatology #diagnosis
Pulmonary Renal Syndrome

Definition: Diffuse alveolar hemorrhage + Glomerulonephritis
Presentation (Pulmonary and renal manifestations can occur weeks apart):
Differential Diagnosis ... Complex: Systemic lupus ... erythematosus, ... #differential #diagnosis ... #nephrology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
pylori test (GI symptoms ... function test, ANA ... anti-phospholipid antibodies ... (CVID, WAS), (neurologic ... changes), high MCV anemia
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
often causes arthritis ... erythematosus, ... Presentation - Systemic Symptoms ... LFT • ESR • ANA ... ) pattern: antibodies