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diagnosis differential management algorithm bruising cll lymphocytic anemia aplastic chemistry cirrhosis common comparison cvid dic diffuse disseminated gap globulin hemeonc
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm Reactive: - Systemic Inflammatory •
Causes of Diffuse ... - History of Bleeding ... (Pancytopenia, WBC ... Age > 50 • Chronic ... #Hematology #Oncology
Causes of Bleeding / Bruising - Differential Diagnosis Algorithm Thrombocytopenia - Quantitative Defect • Decreased Production •
Causes of Bleeding ... - Acquired • Anticoagulation ... Iatrogenic) • Liver ... #Bleeding #Bruising ... #Hematology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
Chronic leukemia ... -> AML: Blast crises ... develop leukostasis syndrome ... • Tumor lysis syndrome ... #Hematology #Oncology
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
promyelocytic leukemia ... organ damage Clinical ... DIC • Severe Liver ... hydration • RBC ... treatment #management #hematology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Chronic Lymphocytic ... Orange or Hep C Clinical ... #CLL #Chronic ... diagnosis #workup #oncology ... #hematology
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
Algorithm Vascular Causes ... vein: Budd-chiari syndrome ... > 2 • NASH, Chronic ... (hemolysis, bleeding ... diagnosis #algorithm #hepatology
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
• Albumin • Coagulation ... > 2 • NASH, Chronic ... (hemolysis, bleeding ... • Gilbert's syndrome ... #differential #Hepatology
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
Chronic Lymphocytic ... immunophenotype Clinical ... Vmphocytosis on routine CBC ... uw_IMresidency #CLL #Chronic ... #oncology #hematology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Aplastic Anemia Clinical ... ecchymoses, mucosal bleeding ... and petechiae Causes ... virus (EBV) • Leukemia ... #hematology #diagnosis
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework == Quantitative or Qualitative defect in
gingivitis or gingival leukemic ... inhibitor of a coagulation ... von Willebrand syndrome ... discern these causes ... Differential #Diagnosis #Hematology
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