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atlas agglutinin aplastic bloodcell chronic classification cold differentiation disease disorders hepatitis hodgkins key leukemia liver lymphocytic lymphoma macrocytic markers mds
Red Blood Cell (RBC) Morphology Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
Red Blood Cell ( ... RBC) Morphology ... Bite Cell RBC: G6PD ... #Morphology #differential ... #diagnosis #hematology
Red Blood Cell (RBC) Morphology Atlas • Microcytic - Iron-deficiency anemia, Thalassemia, Sideroblastic anemia, Lead poisoning
Red Blood Cell ( ... RBC) Morphology ... coagulopathy (DIC) #RBC ... #key #diagnosis ... hematology
Blood Disorders - Markers and Differential Diagnosis Algorithm Acute • Myloid (AML) - CD13, CD33, CD34,
Diagnosis Algorithm ... Acute • Myloid ... bcr-able (+) ↑ WBC ... #Disorders #hematology ... #Diagnosis #Algorithm
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... Diagnosis Algorithm ... #Anemia #Differential ... #Diagnosis #Algorithm ... #workup #hematology
Anemia Diagnostic Algorithm Mean corpuscular (cell) volume (MCV): Average RBC size. Under 80 = microcytic. Between 80-95
Anemia Diagnostic ... (MCV): Average RBC ... High in acute blood ... #Algorithm #Diagnosis ... #Workup #Hematology
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
Acute Liver Injury ... Diagnosis Algorithm ... • Bilirubin: RBC ... #diagnosis #algorithm ... #hepatology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
if high risk if WBC ... QD until normal WBC ... #APML #diagnosis ... #management #hematology ... #oncology
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Cold Agglutinin Syndrome ... Viral Infection Clinical ... Diagnosis: • hemolytic ... smear - RBC agglutination ... #anemia #hematology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Lymphocytosis on CBC ... • Neutropenia, anemia ... ’s lymphoma or acute ... #workup #oncology ... #hematology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Marrow (Toxic injury ... Pancytopenia: • ↓ RBC ... • ↓ WBC • ↓ ... #oncology #hematology ... #diagnosis #management
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