13 results
diagnosis hematology liver algorithm cirrhosis causes lfts morphology pbc primary workup abnormal acute apml bloodcell chemistry cholangitis cll differentiation enzymes
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
Autoimmune hepatitis, PBC ... stone, Malignancy, PBC ... • Bilirubin: RBC ... cardiac muscle, RBC ... • LDH: Heart, RBC
Red Blood Cell (RBC) Morphology Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
Red Blood Cell (RBC ... Morphology Microcytic RBC ... #Morphology #differential ... #diagnosis #hematology ... #microscopy #atlas
Primary Biliary Cirrhosis - Pathophysiology Environmental Risk Factors: Geographic location, Smoking, Microbial triggers, Xenobiotics, Nail polish Epigentics Risk
of autoimmune disease ... relative with PBC ... T-cell mediated BEC injury ... Cholestasis #PBC ... #hepatology
Red Blood Cell (RBC) Morphology Atlas • Microcytic - Iron-deficiency anemia, Thalassemia, Sideroblastic anemia, Lead poisoning
Red Blood Cell (RBC ... ) Morphology Atlas ... coagulopathy (DIC) #RBC ... key #diagnosis #differential ... #hematology
Causes of Acute Liver Injury - Differential Diagnosis Hepatocellular - Liver Parenchyma • Infectious: Hepatitis C, A,
of Acute Liver Injury ... - Differential ... obstruction, HELLP Syndrome ... Malignancy, 1° PBC ... Acute #algorithm #hepatology
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
Cirrhosis (PBC) ... - Summary PBC ... Pathophysiology ... bile ducts Differential ... diagnosis #workup #hepatology
Causes of Fat Malabsorption - Differential Diagnosis Biliary Duct Obstruction • Autoimmune— PBC, PSC • Infection— liver
Malabsorption - Differential ... Diagnosis Biliary ... • Autoimmune— PBC ... - Acquired • Chronic ... • Short bowel syndrome
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
• Bilirubin: RBC ... cardiac muscle, RBC ... • LDH: Heart, RBC ... • Gilbert's syndrome ... #Hepatology #transaminitis
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
ATRA treatment Pathophysiology ... if high risk if WBC ... initiation • Differential ... QD until normal WBC ... #oncology
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
• Heavy Chain disease ... +Organomegaly+↑RBC ... Sneddon-Wilkinson disease ... #Monoclonal #Differential ... #Diagnosis #Oncology
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