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diagnosis hematology differential management anemia algorithm blood causes cll leukemia chronic comparison hemolytic hepatopulmonary lymphocytic workup agglutinin aml aplastic apml
Map of proliferative blood disorders. By Ariella Coler-Reilly @ariellastudies #Algorithm #classification #proliferative #blood #disorders #leukemia #hematology #oncology
proliferative blood disorders ... #Algorithm #classification ... proliferative #blood #disorders ... #leukemia #hematology ... #oncology #diagnosis
Blood Disorders - Markers and Differential Diagnosis Algorithm Acute • Myloid (AML) - CD13, CD33, CD34,
Blood Disorders ... o CML - bcr-able ... (+) ↑ WBC ... o Other bcr-able ... #hematology #Markers
Gastric Neuroendocrine Tumor (NET) Types Type 1 - Chronic atrophic gastritis and pernicious anaemia Type 2 - Zollinger
Zollinger Ellison syndrome ... Tumor #NET #Types #Classification ... #oncology #comparison ... #table
Overall Approach to Anemia - Differential Diagnosis Algorithm Blood Loss • Acute Bleed - Normocytic / Normochromic
RBCs Decreased RBC ... Membrane Disorder ... Disorder - Acquired ... Non-lmmune #Anemia #Classification ... Algorithm #Causes #Hematology
Consensus Indications for Irradiated RBC Transfusions: Cellular blood components are irradiated for the prevention of TA-GVHD. Transfused
for Irradiated RBC ... immunodeficiency disorders ... (DiGeorge Syndrome ... Immunodeficiency Disorder ... #Indications #Hematology
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Normal Blood Smear •
Neutrophils - Low RBC ... • Small Bowel Disorder ... Myelodysplastic Syndromes ... Cells, Normal WBCs ... Algorithm #Causes #Hematology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... if high risk if WBC ... QD until normal WBC ... Differentiation #Syndrome ... #oncology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
) - HELLP syndrome ... Hemolytic uremic syndrome ... lymphoproliferative disorders ... • Intrinsic RBC ... differential #diagnosis #hematology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Constitutional Syndromes ... Pancytopenia: • ↓ RBC ... • ↓ WBC • ↓ ... Aplastic #Anemia #oncology ... #hematology #diagnosis
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Lymphocytosis on CBC ... lymphoproliferative disorders ... • Richter’s Syndrome ... diagnosis #workup #oncology ... #hematology
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