47 results
Hemolytic Anemias - Differential Diagnosis Algorithm

Signs of anemia and hemolysis:
 • ↓ Haptoglobin
 • ↑ LDH
- Differential ... Abnormal peripheral smear ... • Extrinsic RBC ... • Intrinsic RBC ... #Anemias #Differential
Warm Antibody Autoimmune Hemolytic Anemia 
1) DIAGNOSE AIHA
 • Anemia: macrocytic > normocytic, ↑ reticulocytes
 •
Antibody Autoimmune Hemolytic ... reticulocytes • Hemolysis ... ↑ LDH • Anti-RBC ... type ± C3d • Blood ... smear: Differential
Peripheral blood findings in microangiopathic hemolytic anemia.  DIC is a clinical and laboratory diagnosis, not
Peripheral blood ... microangiopathic hemolytic ... arrow) Peripheral smear ... anemia #Hematology #Pathology ... #Smear #Microscopy
Peripheral Blood Smear Analysis
Hypochromia
Megaloblastic Anemia
Schistocytes: Microangiopathic hemolytic anemia (e.g. DIC, TTP, HUS)
Microspherocytes: Autoimmune hemolytic anemia
Sickled red
Peripheral Blood ... Smear Analysis ... Microangiopathic hemolytic ... #Smear #Analysis ... #hematology #microscopy
Babesia spp. on Peripheral Blood Smear Microscopy
 - Multiple small parasites per RBC
 - "maltese cross"
on Peripheral Blood ... Smear Microscopy ... parasites per RBC ... Babesia #clinical #microscopy ... #smear
How to distinguish a metamyelocyte from a band neutrophil.

- Kyle Bradley, MD
@KyleBradleyMD

#Clinical #Pathology #Microscopy #Blood #Smear
KyleBradleyMD #Clinical #Pathology ... #Microscopy #Blood ... #Smear #Peripheral
Pathologic Red Blood Cell (RBC) Morphologies and Associated Diseases

Acanthocyte (spur cell),  
Basophilic stippling, 
Bite cell,
Pathologic Red Blood ... cell, Other RBC ... Morphologies #Key #Atlas #Microscopy ... #Pathology #Hematology ... Robbins & Cotran Pathologic
Hemolytic Anemia - Differential Diagnosis Algorithm
Hereditary:
 • Peripheral blood smear + DAT + further History
 •
Hemolytic Anemia ... - Differential ... • Peripheral blood ... smear + DAT + further ... #Anemia #Differential
Plasmodium Falciparum Blood Smear.
Key features suggesting Plasmodium falciparum:
- extreme parasitemia
- normocytic RBCs (vivax, ovale prefer big
Plasmodium Falciparum Blood ... Smear. ... multiples per RBC ... #Smear. ... peripheral #clinical #microscopy
A normal peripheral blood smear indicates the appropriate appearance of red blood cells, with a zone
normal peripheral blood ... smear indicates ... appearance of red blood ... the size of the RBC ... Clinical #Path #Microscopy