WBC pathophysiology diagnosis causes signs algorithm hepatology complications syndrome anemia cirrhosis dermatology elevatedmcv hemolytic

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11 results

Hemolytic Anemias - Differential Diagnosis Algorithm

Signs of anemia and hemolysis:
• ↓ Haptoglobin
• ↑ LDH

Hemolytic Anemias ... Algorithm Signs ... of anemia and hemolysis ... #Diagnosis #Algorithm ... #hematology

Causes of Anemia with Normal Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Decreased WBCs
- Decreased/NormaI

Causes of Anemia ... Algorithm Decreased ... WBCs - Decreased ... #Algorithm #Causes ... #Hematology

Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Normal Blood Smear
•

Causes of Anemia ... Myelodysplastic Syndromes ... Cells, Normal WBCs ... #Algorithm #Causes ... #Hematology

Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
• Mechanical Trauma (Microangiopathic hemolytic anemia):

Diagnostic Framework ... Extravascular Causes ... anemia): ... • Intrinsic RBC ... #hematology #anemia

Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm
Extravascular - Spleen and RES-mediated hemolysis
-

Causes of Extravascular ... - Differential Diagnosis ... anemia • ... #Algorithm #Causes ... #Hematology

Causes of Anemia with Low Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Decreased Heme Synthesis or

Causes of Anemia ... Algorithm Decreased ... #Macrocytosis #elevatedMCV ... #Algorithm #Causes ... #Hematology

Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
• Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity

blasts and high WBC ... count cause hyperviscosity ... >100k, + lab signs ... #TLS #diagnosis ... #management #hematology

Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury:
• Hepatic vein:

- Differential Diagnosis ... Algorithm Vascular ... Causes of Acute ... hepatitis: < 1 • Cirrhosis ... #algorithm #hepatology

Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
• Lymphocytes accumulate in large numbers

Physical Exam/Signs ... Lymphocytosis on CBC ... • Neutropenia, anemia ... • Richter’s Syndrome ... workup #oncology #hematology

Common Variable Immunodeficiency (CVID)

What?
CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell

noninfectious complications ... and autoimmune hemolytic ... anemia) • Systemic ... DDX - Other causes ... hypogammaglobulinemia #immunology #hematology

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