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management syndrome differential hematology barre caudaequina coagulation cord disorders disseminated equina guillain guillainbarre intravascular leukostasis lysis spinal spinalcord tls tumor
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
blasts and high WBC ... count cause hyperviscosity ... >100k, + lab signs ... hydration - Hyperkalemia ... Syndrome #TLS #diagnosis
Cauda Equina Syndrome Overview Cauda Equina Syndrome: • Prevalence: 1:33,000-100,000 ppl/yr • Incidence: 1.5-3.4 million ppl/yr •
- Emergency Causes ... Differential Diagnosis ... axial T1 and T2 Treatment ... #differential #diagnosis ... #causes #neurology
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
protein C and S Pathophysiology ... Treat primary cause ... hydration • RBC ... #Coagulation #diagnosis ... #causes #treatment
Guillain-Barre Syndrome - Summary Acute AIDP that presents with rapidly progressive flaccid weakness Epidemiology: • 1-2 cases/100,000 per
Epidemiology: • 1-2 cases ... Guillain-Barre Pathophysiology ... - NORMAL CSF WBC ... nerve roots and cauda ... #neurology
Spinal Cord Disorders - Differential Diagnosis Framework Spinal cord neurological lesion: Clinical findings: • Symptoms and signs below
• Symptoms and signs ... Lower roots -> Cauda ... Non-compressive Spinal Cord Causes ... #neurology #differential ... #algorithm
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