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management rheumatology dermatology differential syndrome algorithm causes chronic cll erythematosus leukemia lupus lymphocytic primary pruritus secondary signs sle symptoms workup
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Aplastic Anemia ... • Aplastic anemia ... Anemia Clinical ... #Anemia #oncology ... #hematology #diagnosis
Pruritus - Generalized Differential Diagnosis Algorithm - Systemic and Primary Causes == Primary Skin Lesions == Macules /
Pruritus - Generalized ... Differential Diagnosis ... renal failure/uremia ... Hyperthyroidism CBC ... #generalized #dermatology
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Clinical Features ... of hip (rare), Arthritis ... pain (20%) Renal disease ... ) Blood (75%): Anemia ... signs #symptoms #diagnosis
Primary Sjogren’s Syndrome: Pathogenesis and Clinical Findings • Primary Sjögren's is a solitary process whereas secondary Sjögren's
Pathogenesis and Clinical ... biliary cirrhosis (PBC ... arthritis (RA) ... Sjogrens #Syndrome #Pathophysiology ... #Diagnosis #Signs
Bandemia Overview Normal: < 1% Clinically significant: > 10% Band neutrophils are slightly less mature than segmented neutrophils and
Normal: < 1% Clinically ... • Autoimmune diseases ... likelihood of negative clinical ... #CBC #hematology ... #pathophysiology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
Hepatosplenomegaly and generalized ... idiopathic arthritis ... with leukopenia, anemia ... Activation #Syndrome #Diagnosis ... #Management #Hematology
Sweet Syndrome Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
disease. ... , breast CA - Hematologic ... - CBC may also ... Sweet #Syndrome #diagnosis ... #dermatology #oncology
Pruritus - No Primary Skin Lesion - Differential Diagnosis Algorithm Blood Glucose: • Diabetes Mellitus Liver Function Tests/Enzymes:
- Differential Diagnosis ... renal failure/uremia ... Hyperthyroidism CBC ... Pruritus #secondary #systemic ... #generalized #dermatology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... ) Suspect: Clinical ... Differential Diagnosis ... lymphopenia, low PLT • Anemia ... Erythematosus #Diagnosis
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Orange or Hep C Clinical ... • Neutropenia, anemia ... Pure red cell aplasia ... #workup #oncology ... #hematology
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