34 results
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... blasts and high WBC ... - ACS, AKI, acute ... • Lab values: WBC ... diagnosis #management #hematology
Urticaria (hives): Skin reaction that occurs in response to cold, food allergies, meds, environmental exposures, stings,
infections
Presents as acute ... Can be local or associated ... with systemic symptoms ... Images #Clinical ... #Photo #Dermatology
Bell's Palsy
Bell’s Palsy is a damage, acute weakness, or paralysis of the Facial nerve (7th CN),
Palsy is a damage, acute ... unknown but its clinically ... often associated ... #Bells #Palsy #neurology ... #anatomy #pathophysiology
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
ATRA treatment Pathophysiology ... if high risk if WBC ... Diagnosis: >3 symptoms ... QD until normal WBC ... diagnosis #management #hematology
Bandemia Overview

Normal: < 1%
Clinically significant: > 10%

Band neutrophils are slightly less mature than segmented neutrophils and
Normal: < 1% Clinically ... tachycardia or fever, is associated ... likelihood of negative clinical ... #CBC #hematology ... #pathophysiology
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
Acute Fatty Liver ... Pregnancy (AFLP) Pathophysiology ... postpartum): • Initial symptoms ... headache, malaise) → Acute ... Maternal Support - Critical
Guillain-Barre Syndrome - Summary

Acute AIDP that presents with rapidly progressive flaccid weakness

Epidemiology:
 • 1-2 cases/100,000 per
Syndrome - Summary Acute ... Guillain-Barre Pathophysiology ... - NORMAL CSF WBC ... GQ1b IgG Antibody associated ... management #treatment #neurology
Metformin Associated Lactic Acidosis (MALA) 

Pathophysiology of MALA
 - Metformin interferes with the activity of the
Metformin Associated ... Acidosis (MALA) Pathophysiology ... gastrointestinal distress and acute ... presentation - Clinical ... also includes symptoms
Oncologic Emergencies - Differential Diagnosis Framework

HEMATOLOGIC ONCOLOGIC EMERGENCIES:
Hyperviscosity Syndrome:
 • Spontaneous bleeding
 • Shortness of breath
Diagnosis Framework HEMATOLOGIC ... of breath • Neurologic ... viscosity > 4 cP • Associated ... Leukostasis: • WBC ... Hyperuricemia • Acute
TRALI vs TACO - Transfusion Reactions
TRALI:
 • Epidemiology: 0.1% of transfused patientsl
 • Risk factors: Critical
Risk factors: Critical ... blood donor • Pathophysiology ... ARDS to explain symptoms ... At least 3 of (Acute ... Transfusion #Reactions #hematology