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hematology differential management mds syndromes bee chronic classification cll endocarditis erythematosus hemolytic hodgkins infectiousdiseases leukemia lupus lymphocytic lymphoma myelodysplasia neurology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic ... cytopenias (usually anemia ... transformation to acute ... #treatment #hematology ... #oncology
Warm Antibody Autoimmune Hemolytic Anemia 1) DIAGNOSE AIHA • Anemia: macrocytic > normocytic, ↑ reticulocytes •
Warm Antibody Autoimmune ... 2) LOOK FOR a cause ... → Systematic screening ... #Anemia #diagnosis ... #rheumatology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Aplastic Anemia ... • Aplastic anemia ... anemia Treatment ... #Anemia #oncology ... #hematology #diagnosis
Causes of Thrombocytosis - Differential Diagnosis Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis): • Acute infection • Solid organ
Thrombocytosis): • Acute ... malignancies • Anemia ... disorders (e.g. autoimmune ... syndrome • Myelofibrosis ... #Causes #hematology
BEE Syndromes - Immune-mediated conditions affecting the brain, eye, and ear Visual or auditory symptoms in conjunction
an underlying autoimmune ... and treatment can ... Inflammatory causes ... • Acute disseminated ... encephalomyelitis • MOG antibody-associated
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
Out Secondary Causes ... • Anemia • Aplastic ... treatment (examples ... #Syndromes #diagnosis ... #hematology #oncology
Causes of Neutropenia - Differential Diagnosis Neonate: - Infection - by far the most common cause -
hypertension and/or drug treatment ... - Maternal antibody ... Megaloblastic anemia-rare ... white blood cell aplasia ... #causes #hematology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
• Neutropenia, anemia ... Pure red cell aplasia ... microglobulin Treatment ... ’s lymphoma or acute ... #workup #oncology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
photosensitivity, inflammatory ... Classification: • Acute ... rheumatologic diseases ... lymphopenia, low PLT • Anemia ... #Rheumatology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Immunosuppression • Autoimmune ... Weight loss • Anemia ... platelets - WBC ... Hodgkin Lymphoma Treatment ... #oncology #management
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