14 results
Causes of Thrombocytosis - Differential Diagnosis
Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis):
 • Acute infection
 • Solid organ
malignancies • Anemia ... disorders (e.g. autoimmune ... vera (PV) • Myelodysplastic ... syndrome • Myelofibrosis ... #Causes #hematology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic ... Syndrome (MD) - ... cytopenias (usually anemia ... #treatment #hematology ... #oncology
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Normal Blood Smear
 •
Causes of Anemia ... Dysplastic • Myelodysplastic ... Syndromes Macrocytosis ... #Algorithm #Causes ... #Hematology
Warm Antibody Autoimmune Hemolytic Anemia 
1) DIAGNOSE AIHA
 • Anemia: macrocytic > normocytic, ↑ reticulocytes
 •
1) DIAGNOSE AIHA ... ↑ LDH • Anti-RBC ... 2) LOOK FOR a cause ... → Systematic screening ... #treatment #rheumatology
Pruritus - Generalized Differential Diagnosis Algorithm - Systemic and Primary Causes
== Primary Skin Lesions ==
Macules /
Algorithm - Systemic ... Throbocythemia • Myelodisplastic ... syndrome Psychiatric ... Pruritus #primary #secondary ... #Algorithm #causes
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
DDX: Rule Out Secondary ... CausesAnemia ... treatment (examples ... #Syndromes #diagnosis ... #hematology #oncology
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
and petechiae Causes ... • ↓ WBC • ↓ ... Treatment: ... #oncology #hematology ... #diagnosis #management
Pruritus - No Primary Skin Lesion - Differential Diagnosis Algorithm

Blood Glucose:
 • Diabetes Mellitus
Liver Function Tests/Enzymes:
Throbocythemia • Myelodisplastic ... syndrome Psychiatric ... #Pruritus #secondary ... #systemic #generalized ... #Algorithm #causes
Causes of Neutropenia - Differential Diagnosis
Neonate:
 - Infection - by far the most common cause
 -
- Differential Diagnosis ... hypertension and/or drug treatment ... Chediak-Higashi syndrome ... Megaloblastic anemia-rare ... #causes #hematology
Common Variable Immunodeficiency (CVID)

What?
CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
infection risk secondary ... hemolytic anemia ... ) • Systemic granulomatous ... DDX - Other causes ... : • Nephrotic syndrome