30 results
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 • Mechanical Trauma (Microangiopathic hemolytic anemia):
Diagnostic Framework ... uremic syndrome ... • Intrinsic RBC ... Extravascular #Causes #differential ... #diagnosis #hematology
Hemolytic Anemia - Differential Diagnosis Algorithm
 • Sickle cells - Consider sickle cell disease (diverse genotypes):
- Differential ... Diagnosis Algorithm ... #Anemia #Differential ... #Diagnosis #Algorithm ... #workup #hematology
Workup for Hyperphosphatemia - Differential Diagnosis Framework
Rule out spurious hyperphosphatemia: paraproteinemia, hyperlipidemia, hemolysis, hyperbilirubinemia, liposomal amphotericin
- Differential ... Diagnosis Framework ... Rhabdomyolysis, Tumor lysis syndrome ... acidosis, DKA Kidney Disease ... #nephrology
Hemolysis - Differential Diagnosis Framework

1) Environment
  - Fragmentation
  - MAHA: TTP, HUS, DIC, HELLP
Hemolysis - Differential ... Diagnosis Framework ... Drug-associated, PCH, Evans Syndrome ... #Differential # ... Diagnosis #hematology
Red Blood Cell (RBC) Morphology Atlas
 • Microcytic - Iron-deficiency anemia, Thalassemia, Sideroblastic anemia, Lead poisoning
Myelodysplastic syndrome ... uremic syndrome ... Morphology #Atlas #key #diagnosis ... #differential # ... hematology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
Diagnosis Algorithm ... for workup, including ... blood loss, Acute hemolysis ... Vasculitides, IBD, Celiac disease ... Kawasaki, Nephrotic syndrome
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura

Activity of von Willebrand factor-cleaving protease activity - A
activity is the diagnostic ... hallmark for the disease ... from ischemia WBC ... count and differential ... #Workup #Hematology
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Cold Agglutinin Syndrome ... Viral Infection Clinical ... Diagnosis: • hemolytic ... younger pts) Differential ... #hematology #diagnosis
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
Platelet Disorders - Differential ... Diagnosis and Workup ... PT, aPTT(liver disease ... (CVID, WAS), (neurologic ... #Workup #hematology
Paraproteinemias

Entities That Can Feature A Monoclonal Protein/M Component:
• MM
• WM
• MGUS
• MGCS
• MGRS
• Splenic Marginal Zone
• Heavy Chain disease ... et diutinum Neurologic ... • Coombs (-) hemolytic ... #Monoclonal #Differential ... #Diagnosis #Oncology