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hematology oncology hes anemia aplastic apml classification coagulation dic differentiation disorders disseminated dress eosinophil hodgkins hypereosinophilic intravascular leukostasis lymphoma lysis
Hypereosinophilia and Hypereosinophilic Syndrome • Secondary Hypereosinophilic Syndrome • Clinically Relevant HES Variants • When to
Syndrome • Clinically ... and Treatment Algorithm ... #Hematology #eosinophilia ... #eosinophils #diagnosis ... #management #algorithm
Hypereosinophilia Syndrome (HES) - Diagnosis and Management Definition: An absolute eosinophil count (AEC) greater than 1500 and
than 1500 and clinical ... Secondary Causes ... #eosinophilia #diagnosis ... #hematology #differential ... #management #eosinophils
Eosinophil Disorders Testing Algorithm INDICATIONS FOR TESTING: • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
Eosinophil Disorders ... of eosinophilia ... glucocorticoid treatment ... #Differential # ... diagnosis #hematology
Causes of Eosinophilia - Differential Diagnosis Bugs: - Fungus (aspergillosis) - Viral (HIV) - Ectoparasites (scabies, myiasis)
Causes of Eosinophilia ... Syndrome - Chronic ... Eosinophilic Leukemia ... Diagnosis #Causes ... #hematology
Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS) Definition: • Severe adverse drug reaction, characterized by
Reaction with Eosinophilia ... lymphadenopathy, eosinophilia ... Eosinophilia 4 ... disease: symptomatic treatment ... #dermatology #diagnosis
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
blasts and high WBC ... count cause hyperviscosity ... • Lab values: WBC ... #TLS #diagnosis ... #management #hematology
Pulmonary Renal Syndromes - OnePager Summary Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
polyangiitis), EGPA (eosinophilic ... w differential ... (check eosinophil ... diagnosis #management ... #treatment
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Aplastic Anemia Clinical ... and petechiae Causes ... - Hepatitis, eosinophilic ... Anemia #oncology #hematology ... #diagnosis #management
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... Triggers: ATRA treatment ... Pathophysiology ... initiation • Differential ... #management #hematology
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
protein C and S Pathophysiology ... organ damage Clinical ... #Coagulation #diagnosis ... #causes #treatment ... #management #hematology
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