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diagnosis hematology causes classification algorithm apml differentiation gap globulin high hyperkalemia injury kidney leukemia lupus lymphocytic management mds myelodysplasia myelodysplastic
Acute Kidney Injury (AKI) in Patients with Cancer Cancer Related • Hypercalcemia • Intravenous contrast •
gammopathy of renal ... sinusoidal obstructive syndrome ... Capillary leak syndrome ... • Tumor lysis syndrome ... #Cancer #Oncology
Causes of Acute Kidney Injury (AKI) - Differential Diagnosis Algorithm Acute Kidney Injury (AKI) - Acute increase
) - Differential ... • Hepatorenal syndromes ... Constipation • Prostate Cancer ... #Acute #KidneyInjury ... #Nephrology #Differential
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Leukemia - Summary Cancer ... • Neutropenia, anemia ... aplasia • ITP ... • Richter’s Syndrome ... leukemia • Sezary syndrome
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
Myelodysplastic Syndromes ... • Aplastic Anemia ... Marrow Failure • Chronic ... blood count with differential ... #oncology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... initiation • Differential ... Renal Failure ... Differentiation #Syndrome ... #oncology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
dermatomyositis, Sjogren syndrome ... lymphoma • Evans' syndrome ... lymphoproliferative syndrome ... Shrinking lung syndrome ... APLA/LAC: • Renal
Causes of Hyperkalemia l. Pseudohyperkalemia A Cellular efflux; thrombocytosis, erythrocytosis, leukocytosis, in vitro hemolysis B.
syßtemic lupus erythematosus ... anemia, obstructive ... malignancy, metastatic cancer ... antiphospholipid syndrome ... #Hyperkalemia #Differential
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4) Work-up of an Elevated Globulin Gap: •
changes (POEMS syndrome ... ovarian tumors, lung cancers ... , HCC, renal tumors ... anemia • Other ... Gap #ProteinGap #differential
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