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diagnosis hematology clinical differential msk orthopedics outlet sports thoracic management oncology algorithm anemia causes costoclavicular disease edens hepatopulmonary hyperabduction roos
Approach to the Hypercoagulable State Arterial thromboembolism → Cardiac rhythm monitoring, Echocardiogram, Vascular imaging → Test for APS, particularly
Echocardiogram, Vascular ... imaging → Test ... cancer screening, CBC ... Hypercoagulable #Workup #hematology ... diagnosis #algorithm #hematology
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Normal Blood Smear •
Myelodysplastic Syndromes ... Cells, Normal WBCs ... Liver Function Tests ... Liver Function Tests ... Algorithm #Causes #Hematology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... Triggers: ATRA treatment ... Cathepsin G release → vascular ... if high risk if WBC ... diagnosis #management #hematology
Hemolysis - Differential Diagnosis Framework 1) Environment - Fragmentation - MAHA: TTP, HUS, DIC, HELLP
2) External (RBC ... Drug-associated, PCH, Evans Syndrome ... 3) Internal (RBC ... Laboratory Tests ... Differential #Diagnosis #hematology
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
blasts and high WBC ... • Lab values: WBC ... organ damage • Treatment ... Low calcium • Treatment ... diagnosis #management #hematology
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
Diagnosis Algorithm Vascular ... vein: Budd-chiari syndrome ... extrahepatic source - Tests ... • Gilbert's syndrome ... diagnosis #algorithm #hepatology
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
and diplopia) • Vascular ... Positive pathergy test ... is a skin prick test ... Arthritis, AS Treatment ... signs #symptoms #rheumatology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Constitutional Syndromes ... Pancytopenia: • ↓ RBC ... • ↓ WBC • ↓ ... aplastic anemia Treatment ... Anemia #oncology #hematology
Hepatopulmonary Syndrome - Diagnosis and Management Summary A defect in arterial oxygenation due to a gas exchange
Hepatopulmonary Syndrome ... intrapulmonary vascular ... 10 minutes of rest ... Intra-pulmonary vascular ... #hepatology
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
capillary leak syndrome ... +Organomegaly+↑RBC ... Hypergammaglobulinemic macular ... (Thrombosis in vascular ... Paraproteinemias #Hematology
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