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diagnosis management hematology differential algorithm causes clinical oncology table anemia nephrology neurology workup disease comparison pharmacology vasculitis gastroenterology dermatology pathophysiology
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
blasts and high WBC ... • Lab values: WBC ... organ damage • Treatment ... Low calcium • Treatment ... diagnosis #management #hematology
Blood Product Components, Contents, Volume and Shelf Life Whole blood (autologous or directed donations) - RBC and
WBC and platelets ... Hct of 70-80% - RBC ... X 1010); some WBC ... X 1011); some WBC ... Contents #Volume #Hematology
Hypereosinophilia and Hypereosinophilic Syndrome • Secondary Hypereosinophilic Syndrome • Clinically Relevant HES Variants • When to
Hypereosinophilic Syndrome ... Hypereosinophilic Syndrome ... Diagnosis and Treatment ... Hypereosinophilic #Syndrome ... #HES #Hematology
Nephritic vs Nephrotic Syndrome Step 1: If the patient has hematuria and/or proteinuria, think about nephrotic/nephritic syndromes. Step
Nephritic vs Nephrotic Syndrome ... nephrotic/nephritic syndromes ... glomerular hematuria (RBC ... Nephritic #Nephrotic #Syndrome
Approach to Leukocytosis - Differential Diagnosis Algorithm Features of hematologic malignancy: • Symptoms: B-symptoms, bruising/bleeding, fatigue/weakness, immunosuppression
platelets, persistent WBC ... Diagnosis #Algorithm #hematology ... #WBC #Leukemoid
Interpretation of Components of the CBC (Complete Blood Count) #CBC #Interpretation #CompleteBloodCount #Hematology #Differential #Diagnosis #Laboratory
Components of the CBC ... Blood Count) #CBC ... CompleteBloodCount #Hematology
Aplastic Anemia and Bone Marrow Failure Syndromes with Pancytopenia Fanconi Anemia Acquired Aplastic Anemia Dyskeratosis Congenita & Telemore Biology
Marrow Failure Syndromes ... Shwachman-Diamond Syndrome ... #Pancytopenia #Syndromes ... anemia #diagnosis #Hematology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... Triggers: ATRA treatment ... if high risk if WBC ... Renal Failure Treatment ... QD until normal WBC
Causes of Anemia with Normal Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Decreased WBCs - Decreased/NormaI
Algorithm Decreased WBCs ... Normal/lncreased WBCs ... Polychromatic Macrocytes, RBC ... Spherocytes, RBC ... Algorithm #Causes #Hematology
Sjogren Syndrome - Signs, Symptoms and Diagnosis #Sjogren #Syndrome #Signs #Symptoms #Diagnosis #rheumatology
Sjogren Syndrome ... Diagnosis #Sjogren #Syndrome ... Symptoms #Diagnosis #rheumatology
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