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differential oncology generalized pruritus secondary systemic atlas chronic cll elevatedmcv gap globulin key lymphocytic macrocytosis management mds morphology myelodysplasia myelodysplastic
Causes of Anemia with Normal Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Decreased WBCs - Decreased/NormaI
Causes of Anemia ... Algorithm Decreased ... • Marrow Aplasia ... #Algorithm #Causes ... #Hematology
Causes of Thrombocytopenia - Differential Diagnosis Algorithm Decreased Megakaryopoiesis • Aplastic Anemia • Toxic Damage (e.g.
Causes of Thrombocytopenia ... Anemia • Toxic ... Leukemia, Tumour ... #Algorithm #Causes ... #Hematology
Red Blood Cell (RBC) Morphology Atlas • Microcytic - Iron-deficiency anemia, Thalassemia, Sideroblastic anemia, Lead poisoning
Myelodysplastic syndrome ... Bleeding gastric ulcer ... Thrombotic idiopathic thrombocytopenia ... Morphology #Atlas #key #diagnosis ... #differential #hematology
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Normal Blood Smear •
Causes of Anemia ... Algorithm Normal ... Myelodysplastic Syndromes ... #Algorithm #Causes ... #Hematology
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
Chronic Myelogenous Leukemia ... following EtOH induced thrombocytopenia ... Iron deficiency anemia ... #Algorithm #Causes ... #Hematology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Aplastic Anemia ... • Aplastic anemia ... and petechiae Causes ... virus (EBV) • Leukemia ... #hematology #diagnosis
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
plaques, nodules, ulcers ... • Neutropenia, anemia ... , thrombocytopenia ... #diagnosis #workup ... #oncology #hematology
Pruritus - Generalized Differential Diagnosis Algorithm - Systemic and Primary Causes == Primary Skin Lesions == Macules /
and Primary Causes ... • Lymphoma • Leukemia ... Myelodisplastic syndrome ... #generalized #dermatology ... #Algorithm #causes
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
formed or don’t work ... common cytopenia: Macrocytic ... • Anemia • Aplastic ... Workup: • Complete ... #diagnosis #hematology
Pruritus - No Primary Skin Lesion - Differential Diagnosis Algorithm Blood Glucose: • Diabetes Mellitus Liver Function Tests/Enzymes:
Hyperthyroidism CBC ... • Lymphoma • Leukemia ... Myelodisplastic syndrome ... #generalized #dermatology ... #Algorithm #causes
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