16 results
diagnosis hematology management differential anemia chronic cirrhosis cll leukemia lymphocytic mgus agglutinin algorithm aplastic apml biliary causes cell cholangitis classification
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm Reactive: - Systemic Inflammatory •
(Pancytopenia, WBC ... Lymphocytic Leukemia (CBC ... Lymphocytes) - Monoclonal ... Algorithm #Causes #Hematology ... #Oncology
Monoclonal Gammopathy of Clinical Significance (MGUS) - Differential Diagnosis Neurologic-Centered: (+) Systemic Features: POEMS, AL amyloid, Cryoglobulinemia
Monoclonal Gammopathy ... capillary leak syndrome ... • Schnitzler syndrome ... Differential #Diagnosis #hematology ... #oncology
Multiple Myeloma and Monoclonal Gammopathies C - HyperCalcemia- calcium > 11 mg/dL / >1 mg/dL the ULN R
Multiple Myeloma and Monoclonal ... if this is is monoclonal ... plasmacytoma, POEMs syndrome ... MGUS #diagnosis #hematology ... #oncology
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
Can Feature A Monoclonal ... Amyloidosis and monoclonal ... +Organomegaly+↑RBC ... Paraproteinemias #Hematology ... #Diagnosis #Oncology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... ATRA treatment Pathophysiology ... if high risk if WBC ... QD until normal WBC ... #oncology
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... blasts and high WBC ... • Lab values: WBC ... : • Pathophysiology ... diagnosis #management #hematology
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
) - Summary PBC ... 30-65 years PBC ... Pathophysiology ... cholangitis #diagnosis #workup ... #hepatology
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
- Idiopathic monoclonal ... Cold Agglutinin Syndrome ... malignancy (CLL) - Monoclonal ... Blood smear - RBC ... hemolytic #anemia #hematology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Constitutional Syndromes ... Pancytopenia: • ↓ RBC ... • ↓ WBC • ↓ ... Aplastic #Anemia #oncology ... #hematology #diagnosis
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
Vmphocytosis on routine CBC ... fludarabine) 3) Monoclonal ... Lymphocytic #Leukemia #oncology ... #hematology #hemeonc
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